• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

RSPO2 cdna clone

Scan QR to view Datasheet
Catalog # MBS1272438
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
RSPO2 cdna clone
Product Name

RSPO2, cDNA Clone

Popular Item
Full Product Name

RSPO2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgcgccagt atggagagtg cctgcattcc tgcccatccg ggtactatgg acaccgagcc ccagatatga acagatgtgc aagatgcaga atagaaaact gtgattcttg ctttagcaaa gacttttgta ccaagtgcaa agtaggcttt tatttgcata gaggccgttg ctttgatgaa tgtccagatg gttttgcacc attagaagaa accatggaat gtgtggaagg atgtgaagtt ggtcattgga gcgaatgggg aacttgtagc agaaataatc gcacatgtgg atttaaatgg ggtctggaaa ccagaacacg gcaaattgtt aaaaagccag tgaaagacac aataccgtgt ccaaccattg ctgaatccag gagatgcaag atgacaatga ggcattgtcc aggagggaag agaacaccaa aggcgaagga gaagaggaac aagaaaaaga aaaggaagct gatagaaagg gcccaggagc aacacagcgt cttcctagct acagacagag ctaaccaata a
OMIM
610575
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of RSPO2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for RSPO2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,972 Da
NCBI Official Full Name
Homo sapiens R-spondin 2 homolog (Xenopus laevis), mRNA
NCBI Official Synonym Full Names
R-spondin 2
NCBI Official Symbol
RSPO2  [Similar Products]
NCBI Official Synonym Symbols
CRISTIN2
  [Similar Products]
NCBI Protein Information
R-spondin-2
UniProt Protein Name
R-spondin-2
UniProt Synonym Protein Names
Roof plate-specific spondin-2; hRspo2
Protein Family
UniProt Gene Name
RSPO2  [Similar Products]
UniProt Synonym Gene Names
hRspo2  [Similar Products]
UniProt Entry Name
RSPO2_HUMAN
NCBI Summary for RSPO2
This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
UniProt Comments for RSPO2
R-spondin-2: Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway, probably by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors. Belongs to the R-spondin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Cell development/differentiation

Chromosomal Location of Human Ortholog: 8q23.1

Cellular Component: extracellular region

Molecular Function: protein binding; receptor binding
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000