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SCNN1G recombinant protein :: Amiloride-sensitive sodium channel subunit gamma (SCNN1G) Recombinant Protein

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Catalog # MBS962076
Unit / Price
  1 mg (E-Coli)  /  $1,375 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,835 +2 FREE 8GB USB
SCNN1G recombinant protein
Product Name

Amiloride-sensitive sodium channel subunit gamma (SCNN1G), Recombinant Protein

Full Product Name

Recombinant Human Amiloride-sensitive sodium channel subunit gamma (SCNN1G), partial

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
80-523
Sequence
TVSVSIKVHF RKLDFPAVTI CNINPYKYST VRHLLADLEQ ETREALKSLY GFPESRKRRE AESWNSVSEG KQPRFSHRIP LLIFDQDEKG KARDFFTGRK RKVGGSIIHK ASNVMHIESK QVVGFQLCSN DTSDCATYTF SSGINAIQEW YKLHYMNIMA QVPLEKKINM SYSAEELLVT CFFDGVSCDA RNFTLFHHPM HGNCYTFNNR ENETILSTSM GGSEYGLQVI LYINEEEYNP FLVSSTGAKV IIHRQDEYPF VEDVGTEIET AMVTSIGMHL TESFKLSEPY SQCTEDGSDV PIRNIYNAAY SLQICLHSCF QTKMVEKCGC AQYSQPLPPA ANYCNYQQHP NWMYCYYQLH RAFVQEELGC QSVCKEACSF KEWTLTTSLA QWPSVVSEKW LLPVLTWDQG RQVNKKLNKT DLAKLLIFYK DLNQRSIMES PANS
OMIM
177200
3D Structure
ModBase 3D Structure for P51170
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of SCNN1G recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SCNN1G. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
74,270 Da
NCBI Official Full Name
amiloride-sensitive sodium channel subunit gamma
NCBI Official Synonym Full Names
sodium channel epithelial 1 gamma subunit
NCBI Official Symbol
SCNN1G  [Similar Products]
NCBI Official Synonym Symbols
PHA1; BESC3; ENaCg; SCNEG; ENaCgamma
  [Similar Products]
NCBI Protein Information
amiloride-sensitive sodium channel subunit gamma
UniProt Protein Name
Amiloride-sensitive sodium channel subunit gamma
UniProt Synonym Protein Names
Epithelial Na(+) channel subunit gamma; ENaCG; Gamma-ENaC; Gamma-NaCH; Nonvoltage-gated sodium channel 1 subunit gamma; SCNEG
UniProt Gene Name
SCNN1G  [Similar Products]
UniProt Synonym Gene Names
ENaCG; Gamma-ENaC  [Similar Products]
NCBI Summary for SCNN1G
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome. [provided by RefSeq, Apr 2009]
UniProt Comments for SCNN1G
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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