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SCTR recombinant protein :: Secretin receptor (SCTR) Recombinant Protein

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Catalog # MBS947954
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SCTR recombinant protein
Product Name

Secretin receptor (SCTR), Recombinant Protein

Full Product Name

Recombinant Human Secretin receptor (SCTR)

Product Synonym Names
Recombinant Secretin receptor (SCTR); Secretin receptor; SCT-R
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
23-440
Sequence
HSTGALPRLC DVLQVLWEEQ DQCLQELSRE QTGDLGTEQP VPGCEGMWDN ISCWPSSVPG RMVEVECPRF LRMLTSRNGS LFRNCTQDGW SETFPRPNLA CGVNVNDSSN EKRHSYLLKL KVMYTVGYSS SLVMLLVALG ILCAFRRLHC TRNYIHMHLF VSFILRALSN FIKDAVLFSS DDVTYCDAHR AGCKLVMVLF QYCIMANYSW LLVEGLYLHT LLAISFFSER KYLQGFVAFG WGSPAIFVAL WAIARHFLED VGCWDINANA SIWWIIRGPV ILSILINFIL FINILRILMR KLRTQETRGN EVSHYKRLAR STLLLIPLFG IHYIVFAFSP EDAMEIQLFF ELALGSFQGL VVAVLYCFLN GEVQLEVQKK WQQWHLREFP LHPVASFSNS TKASHLEQSQ GTCRTSII
Chromosome Location
Chromosome: 2; NC_000002.11 (120197419..120282028, complement). Location: 2q14.1
OMIM
182098
3D Structure
ModBase 3D Structure for P47872
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of SCTR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SCTR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
50,207 Da[Similar Products]
NCBI Official Full Name
secretin receptor
NCBI Official Synonym Full Names
secretin receptor
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
secretin receptor; pancreatic secretin receptor
UniProt Protein Name
Secretin receptor
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
SCT-R  [Similar Products]
UniProt Entry Name
SCTR_HUMAN
NCBI Summary for SCTR
The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008]
UniProt Comments for SCTR
SCTR: This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q14.1

Cellular Component: integral to plasma membrane; cytoplasmic microtubule; plasma membrane

Molecular Function: secretin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; digestion; excretion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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