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SEPW1 recombinant protein :: Selenoprotein W (SEPW1) Recombinant Protein

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Catalog # MBS1328480
Unit / Price
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  0.05 mg (E-Coli)  /  $475 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $630 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $635 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $700 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $860 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $870 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $970 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,050 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,105 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,245 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,535 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,640 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,810 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,560 +3 FREE 8GB USB
SEPW1 recombinant protein
Product Name

Selenoprotein W (SEPW1), Recombinant Protein

Full Product Name

Recombinant Macaca mulatta (Rhesus macaque) Selenoprotein W (SEPW1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-87@aa, Full Length of Mature Protein
Sequence
ALAVRVVYCG AUGYKSKYLQ LKKKLEDEFP GRLDICGEGT PQATGFFEVM VAGKLIHSKK KGDGYVDTES KFLKLVAAIK AALAQG
3D Structure
ModBase 3D Structure for P63303
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Macaca mulatta (Rhesus macaque)
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of SEPW1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SEPW1 recombinant protein
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein shows highest expression in skeletal muscle and heart, and may be involved in oxidation-reduction reactions. A retroprocessed pseudogene, SEPW1P, has been identified and mapped to chromosome 1p35-34.
NCBI/Uniprot data below describe general gene information for SEPW1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
9,448 Da
NCBI Official Full Name
selenoprotein W
NCBI Official Symbol
SELENOW  [Similar Products]
NCBI Official Synonym Symbols
SEPW1
  [Similar Products]
NCBI Protein Information
selenoprotein W
UniProt Protein Name
Selenoprotein W
Protein Family
UniProt Gene Name
SELENOW  [Similar Products]
UniProt Synonym Gene Names
NCBI Summary for SEPW1
This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is highly expressed in skeletal muscle, heart and brain. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Studies in mouse show that this selenoprotein is involved in muscle growth and differentiation, and in the protection of neurons from oxidative stress during neuronal development. A pseudogene of this locus has been identified on chromosome 1. [provided by RefSeq, Aug 2017]
UniProt Comments for SEPW1
Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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