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SERPINA3 antigen :: Alpha 1 Antichymotrypsin Antigen

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Catalog # MBS568719
Unit / Price
  0.3 mg  /  $365 +1 FREE 8GB USB
SERPINA3 antigen
Product Name

Alpha 1 Antichymotrypsin (SERPINA3), Antigen

Also Known As

Alpha 1 Antichymotrypsin Antigen >=95%

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
423
OMIM
107280
Host
Human Plasma
Purity/Purification
>=95% by SDS-PAGE
Form/Format
Lyophilized from 20 mM Tris-HCl, pH 7.4 with 150 mM NaCl
Preparation and Storage
Store at <=-20 degree C
Other Notes
Small volumes of SERPINA3 antigen vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for SERPINA3 antigen
Applications Tested/Suitable for SERPINA3 antigen
Immunogen Grade
NCBI/Uniprot data below describe general gene information for SERPINA3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,717 Da[Similar Products]
NCBI Official Full Name
alpha-1-antichymotrypsin
NCBI Official Synonym Full Names
serpin family A member 3
NCBI Official Symbol
SERPINA3  [Similar Products]
NCBI Official Synonym Symbols
ACT; AACT; GIG24; GIG25
  [Similar Products]
NCBI Protein Information
alpha-1-antichymotrypsin
UniProt Protein Name
Alpha-1-antichymotrypsin
UniProt Synonym Protein Names
Cell growth-inhibiting gene 24/25 protein; Serpin A3
Protein Family
UniProt Gene Name
SERPINA3  [Similar Products]
UniProt Synonym Gene Names
AACT; ACT  [Similar Products]
UniProt Entry Name
AACT_HUMAN
NCBI Summary for SERPINA3
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]
UniProt Comments for SERPINA3
SERPINA3: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Belongs to the serpin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q32.1

Cellular Component: extracellular region; extracellular space; nucleus

Molecular Function: DNA binding; protein binding; serine-type endopeptidase inhibitor activity

Biological Process: platelet degranulation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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