• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SFTPC recombinant protein :: Pulmonary surfactant-associated protein C (SFTPC) Recombinant Protein

Scan QR to view Datasheet
Catalog # MBS963062
Unit / Price
  0.01 mg (E-Coli)  /  $160 +1 FREE 8GB USB
  0.01 mg (Yeast)  /  $175 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $200 +1 FREE 8GB USB
  0.01 mg (Mammalian-Cell)  /  $225 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $225 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $295 +1 FREE 8GB USB
  0.02 mg (Mammalian-Cell)  /  $335 +1 FREE 8GB USB
  0.1 mg (Yeast)  /  $355 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $480 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $565 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $635 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $770 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $790 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $880 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $925 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $975 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,215 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,410 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,410 +1 FREE 8GB USB
  1 mg (Baculovirus)  /  $1,895 +2 FREE 8GB USB
SDS-PAGE
Product Name

Pulmonary surfactant-associated protein C (SFTPC), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human Pulmonary surfactant-associated protein C (SFTPC)

Product Synonym Names
Pulmonary surfactant-associated proteolipid SPL(Val); SP5
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS963062 COA
Sequence Positions
24-58. Full Length of Mature Protein
Sequence
FGIPCCPVHL KRLLIVVVVV VLIVVVIVGA LLMGL
OMIM
178620
3D Structure
ModBase 3D Structure for P11686
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of SFTPC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SFTPC recombinant protein
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
Product Categories/Family for SFTPC recombinant protein

SFTPC recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for SFTPC. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30.39kD
NCBI Official Full Name
pulmonary surfactant-associated protein C isoform 2
NCBI Official Synonym Full Names
surfactant protein C
NCBI Official Symbol
SFTPC  [Similar Products]
NCBI Official Synonym Symbols
SP-C; PSP-C; SFTP2; SMDP2; BRICD6
  [Similar Products]
NCBI Protein Information
pulmonary surfactant-associated protein C
UniProt Protein Name
Pulmonary surfactant-associated protein C
UniProt Synonym Protein Names
Pulmonary surfactant-associated proteolipid SPL(Val); SP5
UniProt Gene Name
SFTPC  [Similar Products]
UniProt Synonym Gene Names
SFTP2; SP-C  [Similar Products]
UniProt Entry Name
PSPC_HUMAN
NCBI Summary for SFTPC
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]
UniProt Comments for SFTPC
SFTPC: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. Defects in SFTPC are the cause of pulmonary surfactant metabolism dysfunction type 2 (SMDP2); also called pulmonary alveolar proteinosis due to surfactant protein C deficiency. A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Genetic variations in SFTPC are a cause of susceptibility to respiratory distress syndrome in premature infants (RDS); also known as RDS in prematurity. RDS is a lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called 'hyaline membranes'. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: clathrin-coated endocytic vesicle; endoplasmic reticulum membrane; extracellular region; extracellular space; lamellar body

Molecular Function: protein binding

Biological Process: cellular protein metabolic process; respiratory gaseous exchange

Disease: Pulmonary Fibrosis, Idiopathic; Surfactant Metabolism Dysfunction, Pulmonary, 2
Product References and Citations for SFTPC recombinant protein
"Low molecular weight human pulmonary surfactant protein (SP5): isolation, characterization, and cDNA and amino acid sequences." Warr R.G., Hawgood S., Buckley D.I., Crisp T.M., Schilling J., Benson B.J., Ballard P.L., Clements J.A., White R.T. Proc. Natl. Acad. Sci. U.S.A. 84:7915-7919(1987)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with SFTPC recombinant protein
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000