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SGLT2 positive control

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Catalog # MBS543251
Unit / Price
  5 Applications  /  $290 +1 FREE 8GB USB
SGLT2 positive control
Product Name

SGLT2, Positive Control

Popular Item
Also Known As

SGLT2 Positive Control

Product Synonym Names
Low affinity sodium glucose cotransporter; Na(+) glucose cotransporter 2; SGLT 2; SLC5A2; Sodium glucose cotransporter 2; Solute carrier family 5 (sodium glucose cotransporter) member 2 antibodySolute carrier family 5 member 2 antibody
Matching Pairs
Antibody: SGLT2 (MBS544866)
Positive Control: SGLT2 (MBS543251)
Matching Pairs
Antibody: SGLT2 (MBS544867)
Positive Control: SGLT2 (MBS543251)
Matching Pairs
Antibody: SGLT2 (MBS544868)
Positive Control: SGLT2 (MBS543251)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
672
OMIM
182381
3D Structure
ModBase 3D Structure for P31639
Form/Format
Western Blot Positive Control in ready to use SDS-sample buffer
Immunogen
Purified Protein
Preparation and Storage
Store at -20°C for long term storage
Other Notes
Small volumes of SGLT2 positive control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SGLT2 positive control
Western Blot Positive Control Sodium/glucose cotransporter 2
Sodium-dependent glucose transporter. Has a Na+ to glucose coupling ratio of 1:1.
Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na+/glucose cotransporter arranged in series along kidney proximal tubules.
Applications Tested/Suitable for SGLT2 positive control
Western Blot (WB)
Application Notes for SGLT2 positive control
Western Blot: 1:500
NCBI/Uniprot data below describe general gene information for SGLT2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
sodium/glucose cotransporter 2
NCBI Official Synonym Full Names
solute carrier family 5 member 2
NCBI Official Symbol
SLC5A2  [Similar Products]
NCBI Official Synonym Symbols
SGLT2
  [Similar Products]
NCBI Protein Information
sodium/glucose cotransporter 2
UniProt Protein Name
Sodium/glucose cotransporter 2
UniProt Synonym Protein Names
Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2
UniProt Gene Name
SLC5A2  [Similar Products]
UniProt Synonym Gene Names
SGLT2; Na(+)/glucose cotransporter 2  [Similar Products]
UniProt Entry Name
SC5A2_HUMAN
NCBI Summary for SGLT2
This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015]
UniProt Comments for SGLT2
SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: brush border membrane; integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: glucose:sodium symporter activity; low-affinity glucose:sodium symporter activity

Biological Process: carbohydrate metabolic process; sodium ion transport; transport

Disease: Renal Glucosuria
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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