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SHBG native protein

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Catalog # MBS537806
Unit / Price
  1 mg  /  $1,415 +1 FREE 8GB USB
SHBG native protein
Product Name

SHBG, Native Protein

Popular Item
Also Known As

SHBG protein

Product Synonym Names
Sex Hormone Binding Globulin protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
402
OMIM
182205
Purity/Purification
> 90% pure
Form/Format
Supplied lyophilized from 20mM NH4HCO3. May contain traces of buffer salts. Reconstitute with Phosphate buffer, with 150mM Sodium Chloride, pH >7.0.
Concentration
1.0mg per vial; lyophilized (lot specific)
Source
Normal Serum/Human plasma
Species
Human
Grade
Highly Pure
Protein Type
Native
Biological Significance
SHBG transports the sex steroids testosterone, DHT and estradiol in the blood. Serum levels are increased during pregnancy, in women taking estrogens, and in men over the age of 50. Levels are reduced after menopause and in response to treatment with androgens or corticosteroids. Diagnostic uses include polycystic ovary disease and tests for liver and thyroid function.
Contaminants
SDS-PAGE shows a major band corresponding to a molecular weight of approximately 45 kD.
Biohazard
Raw material tested at the donor level anf found negative for HIV I& II antibodies, HCV antibodies and HBsAg by FDA approved methods.
Preparation and Storage
Ships at 4 degree C, upon receipt store at -70 degree C long term. Avoid repeated freeze/thaw cycles
Other Notes
Small volumes of SHBG native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SHBG native protein
Purified native Human SHBG protein
Applications Tested/Suitable for SHBG native protein
User optimized
NCBI/Uniprot data below describe general gene information for SHBG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Secondary Accession #
NCBI Official Full Name
sex hormone-binding globulin
UniProt Protein Name
Sex hormone-binding globulin
UniProt Synonym Protein Names
Sex steroid-binding protein; SBP; Testis-specific androgen-binding protein; ABP; Testosterone-estradiol-binding globulin; TeBG; Testosterone-estrogen-binding globulin
UniProt Gene Name
UniProt Synonym Gene Names
SHBG; SBP; ABP; TeBG  [Similar Products]
UniProt Entry Name
SHBG_HUMAN
UniProt Comments for SHBG
SHBG: Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: extracellular region

Molecular Function: androgen binding

Biological Process: primary spermatocyte growth
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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