NP_001032420.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
107,519 Da
NCBI Official Full Name
cyclin-dependent kinase-like 5
NCBI Official Synonym Full Names
cyclin-dependent kinase-like 5
NCBI Protein Information
cyclin-dependent kinase-like 5; serine/threonine kinase 9; serine/threonine-protein kinase 9; cyclin dependent kinase 5 transcript
UniProt Protein Name
Cyclin-dependent kinase-like 5
UniProt Synonym Protein Names
Serine/threonine-protein kinase 9
UniProt Synonym Gene Names
UniProt Entry Name
CDKL5_HUMAN
NCBI Summary for CDKL5
This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
UniProt Comments for CDKL5
CDKL5: a protein kinase of the CDKL family. Mutations have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.
Protein type: Protein kinase, Ser/Thr (non-receptor); Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Protein kinase, CMGC; CMGC group; CDKL family
Chromosomal Location of Human Ortholog: Xp22
Cellular Component: nucleoplasm; dendrite cytoplasm; cytoplasm; nucleus
Molecular Function: protein serine/threonine kinase activity; cyclin-dependent protein kinase activity; Rac GTPase binding; kinase activity; ATP binding; protein kinase activity
Biological Process: regulation of cell cycle; positive regulation of axon extension; protein amino acid autophosphorylation; neuron migration; regulation of dendrite development; positive regulation of dendrite morphogenesis; protein amino acid phosphorylation
Disease: Angelman Syndrome; Epileptic Encephalopathy, Early Infantile, 2
Research Articles on CDKL5
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with CDKL5 elisa kit
Pathways associated with CDKL5 elisa kit
Diseases associated with CDKL5 elisa kit
Organs/Tissues associated with CDKL5 elisa kit
|