• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Sirt2 elisa kit :: Rat NAD-dependent deacetylase sirtuin-2 ELISA Kit

Scan QR to view Datasheet
Catalog # MBS2881347
Unit / Price
Scan QR to view Datasheet
  48-Strip-Wells  /  $355 +1 FREE 8GB USB
  96-Strip-Wells  /  $475 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,030 +2 FREE 8GB USB
  10x96-Strip-Wells  /  $3,700 +4 FREE 8GB USB
Sirt2 elisa kit
Product Name

NAD-dependent deacetylase sirtuin-2 (Sirt2), ELISA Kit

Full Product Name

Rat NAD-dependent deacetylase sirtuin-2 ELISA Kit

Product Synonym Names
NAD-dependent deacetylase sirtuin-2; SIR2-like protein 2; Sirt2; Sir2l2
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
3D Structure
ModBase 3D Structure for Q5RJQ4
Species Reactivity
Assay Type
Sandwich
Detection Range
0.312-20 ng/mL
Sensitivity
0.157 ng/mL
Intra-Assay CV
<=4.8%
Inter-Assay CV
<=8.2%
Recovery
102%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of Sirt2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Sirt2purchase
MBS2881347 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the NAD-dependent deacetylase sirtuin-2 (Sirt2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Sirt2. The ELISA analytical biochemical technique of the MBS2881347 kit is based on Sirt2 antibody-Sirt2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Sirt2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Sirt2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for Sirt2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
39,319 Da
NCBI Official Full Name
NAD-dependent protein deacetylase sirtuin-2
NCBI Official Synonym Full Names
sirtuin 2
NCBI Official Symbol
Sirt2  [Similar Products]
NCBI Protein Information
NAD-dependent protein deacetylase sirtuin-2
UniProt Protein Name
NAD-dependent protein deacetylase sirtuin-2
UniProt Synonym Protein Names
Regulatory protein SIR2 homolog 2; SIR2-like protein 2
UniProt Gene Name
Sirt2  [Similar Products]
UniProt Synonym Gene Names
Sir2l2  [Similar Products]
UniProt Entry Name
SIR2_RAT
UniProt Comments for Sirt2
SIRT2: NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA. Interacts with HDAC6, suggesting that these proteins belong to a large complex that deacetylate the cytoskeleton. Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network. Inhibited by Sirtinol, A3 and M15 small molecules. Inhibited by nicotinamide. Belongs to the sirtuin family. Class I subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.5.1.-; Deacetylase

Cellular Component: centriole; centrosome; chromosome; cytoplasm; cytosol; growth cone; lateral loop; microtubule; midbody; myelin sheath; nuclear heterochromatin; nucleus; paranode region of axon; perikaryon; perinuclear region of cytoplasm; plasma membrane; spindle

Molecular Function: beta-tubulin binding; chromatin binding; histone acetyltransferase binding; histone deacetylase activity; histone deacetylase binding; NAD-dependent histone deacetylase activity; NAD-dependent histone deacetylase activity (H4-K16 specific); protein deacetylase activity; transcription factor binding; tubulin deacetylase activity; ubiquitin binding; zinc ion binding

Biological Process: autophagy; cell division; cellular lipid catabolic process; central nervous system development; hepatocyte growth factor receptor signaling pathway; histone deacetylation; meiotic cell cycle; mitosis; myelination in the peripheral nervous system; negative regulation of apoptosis; negative regulation of autophagy; negative regulation of cell proliferation; negative regulation of fat cell differentiation; negative regulation of oligodendrocyte differentiation; negative regulation of protein catabolic process; negative regulation of striated muscle development; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; phosphoinositide 3-kinase cascade; positive regulation of attachment of spindle microtubules to kinetochore; positive regulation of cell division; positive regulation of DNA binding; positive regulation of meiosis; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of transcription from RNA polymerase II promoter; proteasomal ubiquitin-dependent protein catabolic process; protein amino acid deacetylation; protein kinase B signaling cascade; regulation of cell cycle; regulation of fat cell differentiation; regulation of myelination; substantia nigra development; transcription, DNA-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000