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Slc1a2 recombinant protein :: Excitatory amino acid transporter 2 Recombinant Protein

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Catalog # MBS968106
Unit / Price
  0.01 mg (Yeast)  /  $110 +1 FREE 8GB USB
  0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $190 +1 FREE 8GB USB
  0.1 mg (Yeast)  /  $285 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $460 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $750 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
SDS-PAGE
Product Name

Excitatory amino acid transporter 2 (Slc1a2), Recombinant Protein

Popular Item
Also Known As

Recombinant Mouse Excitatory amino acid transporter 2

Product Synonym Names
GLT-1; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
143-238aa; Extracellular Domain
Sequence Length
572
Sequence
HPGNPKLKKQ LGPGKKNDEV SSLDAFLDLI RNLFPENLVQ ACFQQIQTVT KKVLVAPPSE EANTTKAVIS MLNETMNEAP EETKIVIKKG LEFKDG
3D Structure
ModBase 3D Structure for P43006
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Slc1a2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Slc1a2 recombinant protein
Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly roving released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.

Slc1a2 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Slc1a2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38kD
NCBI Official Full Name
excitatory amino acid transporter 2 isoform 1
NCBI Official Synonym Full Names
solute carrier family 1 (glial high affinity glutamate transporter), member 2
NCBI Official Symbol
Slc1a2  [Similar Products]
NCBI Official Synonym Symbols
GLT1; Eaat2; GLT-1; MGLT1; AI159670; 1700091C19Rik; 2900019G14Rik
  [Similar Products]
NCBI Protein Information
excitatory amino acid transporter 2
UniProt Protein Name
Excitatory amino acid transporter 2
UniProt Synonym Protein Names
GLT-1; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2
UniProt Gene Name
Slc1a2  [Similar Products]
UniProt Synonym Gene Names
Eaat2; Glt1  [Similar Products]
UniProt Entry Name
EAA2_MOUSE
UniProt Comments for Slc1a2
GLT1: an integral membrane protein belonging to the sodium:dicarboxylate (SDF) symporter family. Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by co-transporting sodium.

Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; Transporter

Cellular Component: axolemma; axon; cell surface; dendritic shaft; dendritic spine; integral to membrane; integral to plasma membrane; membrane; neuron projection; plasma membrane; presynaptic membrane; synapse

Molecular Function: anion transmembrane transporter activity; glutamate:sodium symporter activity; high-affinity glutamate transmembrane transporter activity; L-glutamate transmembrane transporter activity; sodium:dicarboxylate symporter activity; symporter activity

Biological Process: adult behavior; cellular response to extracellular stimulus; dicarboxylic acid transport; L-glutamate import; L-glutamate transport; multicellular organism growth; multicellular organismal aging; nervous system development; positive regulation of glucose import; response to amino acid stimulus; response to drug; response to light stimulus; response to wounding; telencephalon development; transport; visual behavior
Product References and Citations for Slc1a2 recombinant protein
Mouse excitatory amino acid transporter EAAT2 isolation, characterization, and proximity to neuroexcitability loci on mouse chromosome 2.Kirschner M.A., Copeland N.G., Gilbert D.J., Jenkins N.A., Amara S.G.Genomics 24:218-224(1994) Molecular cloning of two glutamate transporter subtypes from mouse brain.Mukainaka Y., Tanaka K., Hagiwara T., Wada K.Biochim. Biophys. Acta 1244:233-237(1995) Molecular characterization of a high-affinity mouse glutamate transporter.Sutherland M.L., Delaney T.A., Noebels J.L.Gene 162:271-274(1995) Peng J.-B., Guo L.-H. Tissue specific variants of glutamate transporter GLT-1.Utsunomiya-Tate N., Endou H., Kanai Y.FEBS Lett. 416:312-316(1997) Lubec G., Kang S.U.Submitted (APR-2007) to UniProtKB Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.J. Proteome Res. 7:311-318(2008) Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease.Huang K., Kang M.H., Askew C., Kang R., Sanders S.S., Wan J., Davis N.G., Hayden M.R.Neurobiol. Dis. 40:207-215(2010)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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