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SLC3A2 recombinant protein :: 4F2 cell-surface antigen heavy chain (SLC3A2) Recombinant Protein

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Catalog # MBS1486683
Unit / Price
Scan QR to view Datasheet
  0.5 mg (E-Coli)  /  $1,200 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,200 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,420 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,420 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,935 +2 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,935 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,400 +3 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,400 +3 FREE 8GB USB
SLC3A2 recombinant protein
Product Name

4F2 cell-surface antigen heavy chain (SLC3A2), Recombinant Protein

Full Product Name

Recombinant Rabbit 4F2 cell-surface antigen heavy chain (SLC3A2), partial

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
106-529
Sequence
RAPRC RELPVQRWWH KGALYRVGDL QAFQARDSGD LAGLKGHLDY LSTLKVKGLV LGPIHKNQED DVAGTNLQEI NPAVGSKEEF DSFLQSAKKK SIRVILDLTP NYLGQNSWFL PTQVDLVATK VKDALNFWLQ AGVDGFQVRD VGNLTNAALH LAEWRNITKS FSEDRLLIAG TESSDLHQIL SLLESTKDLL LTSSYLSASG VSGENMKFLV TQYLNATDSH WCSWSLSQAG LLTSFVPAQL LRLYQLLLFT LPGTPVFSYG DEIGLQAAAL PGEPAKAPVM LWDESSLPSA SVSANMTVKG QDEDSGSLLS LFRRLSDQRG KERSLLHGDF HALSTGSNLF SYVRHWDQNE RFLVVLNFGD ESLSARLGAS SLPAGASLPA RADLLLSTHP GREEGTSLAL EHLNLEPHEG LLLHFPYVA
3D Structure
ModBase 3D Structure for Q7YQK3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rabbit
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SLC3A2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SLC3A2 recombinant protein
This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein with an alpha amylase domain. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. It associates with integrins and mediates integrin-dependent signaling related to normal cell growth and tumorigenesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NCBI/Uniprot data below describe general gene information for SLC3A2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
57,795 Da
NCBI Official Full Name
4F2 cell-surface antigen heavy chain
NCBI Official Symbol
SLC3A2  [Similar Products]
NCBI Protein Information
4F2 cell-surface antigen heavy chain
UniProt Protein Name
4F2 cell-surface antigen heavy chain
UniProt Synonym Protein Names
Solute carrier family 3 member 2; CD_antigen: CD98
Protein Family
UniProt Gene Name
SLC3A2  [Similar Products]
UniProt Synonym Gene Names
4F2hc  [Similar Products]
UniProt Comments for SLC3A2
Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier. When associated with LAPTM4B, recruits SLC3A2 and SLC7A5 to lysosomes to promote leucine uptake into these organelles and is required for mTORC1 activation ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with SLC3A2 recombinant protein
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