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SLC7A7 elisa kit :: Monkey Y+L amino acid transporter 1 (SLC7A7) ELISA Kit

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Catalog # MBS7228917
Unit / Price
  48-Strip-Wells  /  $440 +1 FREE 8GB USB
  96-Strip-Wells  /  $640 +1 FREE 8GB USB
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SLC7A7 elisa kit
Product Name

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit

Also Known As

Monkey Y+L amino acid transporter 1 (SLC7A7) ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
603593
Species Reactivity
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Assay Type
Competitive
Detection Range
1.0-25ng/mL
Sensitivity
0.1ng/mL
Preparation and Storage
Store all reagents at 2-8 degree C.
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of SLC7A7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forSLC7A7purchase
MBS7228917 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Y+L amino acid transporter 1 (SLC7A7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SLC7A7. The ELISA analytical biochemical technique of the MBS7228917 kit is based on SLC7A7 antibody-SLC7A7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC7A7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC7A7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for SLC7A7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55,991 Da[Similar Products]
NCBI Official Full Name
Y+L amino acid transporter 1
NCBI Official Synonym Full Names
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
NCBI Official Symbol
SLC7A7  [Similar Products]
NCBI Official Synonym Symbols
LPI; LAT3; MOP-2; Y+LAT1; y+LAT-1
  [Similar Products]
NCBI Protein Information
Y+L amino acid transporter 1; Y+L amino acid transporter 1; monocyte amino acid permease 2; y(+)L-type amino acid transporter 1; solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
UniProt Protein Name
Y+L amino acid transporter 1
UniProt Synonym Protein Names
Monocyte amino acid permease 2; MOP-2; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1
UniProt Gene Name
SLC7A7  [Similar Products]
UniProt Synonym Gene Names
MOP-2; Y+LAT1; y+LAT-1  [Similar Products]
UniProt Entry Name
YLAT1_HUMAN
NCBI Summary for SLC7A7
The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]
UniProt Comments for SLC7A7
SLC7A7: Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L- arginine in monocytes. Defects in SLC7A7 are the cause of lysinuric protein intolerance (LPI). LPI is an autosomal recessive multisystem disorder found mainly in Finland and Italy. On a normal diet, LPI patients present poor feeding, vomiting, diarrhea, episodes of hyperammoniaemic coma and growth retardation. Hepatosplenomegaly, osteoporosis and a life- threatening pulmonary involvement (alveolar proteinosis) are also seen. Biochemically LPI is characterized by a defect in the plasma membrane transport of dibasic amino acids. Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: integral to plasma membrane; basolateral plasma membrane; plasma membrane

Molecular Function: amino acid transmembrane transporter activity

Biological Process: amino acid metabolic process; amino acid transport; transport; protein complex assembly; ion transport; blood coagulation; leukocyte migration; transmembrane transport

Disease: Lysinuric Protein Intolerance
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withSLC7A7 elisa kit
 Reference Product  PubMed Publications
 SLC3A2 elisa kit  >6 publications with SLC7A7 and SLC3A2
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