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SORBS2 cdna clone

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Catalog # MBS1271733
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $285 +1 FREE 8GB USB
SORBS2 cdna clone
Product Name

SORBS2, cDNA Clone

Popular Item
Full Product Name

SORBS2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgagttact atcagaggcc gttttccccc tcggcatatt ctctcccagc ctcactcaac tccagcattg tcatgcagca cggcacatcc ctcgattcca cagacacata tccccagcat gcgcagtctc tggatggcac caccagcagc tctatccccc tgtaccgatc ctcagaggaa gagaagagag tgacagtcat caaagccccg cattacccag ggatcgggcc cgtggatgaa tccggaatcc ccacagcaat tagaacgaca gtcgaccggc ccaaggactg gtacaagacg atgtttaagc aaattcacat ggtgcacaag ccggatgatg acacagacat gtataatact ccttatacat acaatgcagg tctgtacaac ccaccctaca gtgctcagtc acaccctgct gcaaagaccc aaacctacag acctctttcc aaaagccact ccgacaacag ccccaatgcc tttaaggatg cgtcctcccc agtgcctccc ccacatgttc cacctccagt cccgccgctt cgaccaagag atcggtcttc aacagaaaag catgactggg atcctccaga cagaaaagtg gacacaagaa aatttcggtc tgagccaagg agtatttttg aatatgaacc tggcaagtca tcaattcttc agcatgaaag accaccccct ctcccaacaa ctccgacacc tgttccaagg gaacctggcc ggaagcctct ttctagctcc cgactcggag aagtcactgg tagcccctcc cctccgcccc ggagtggcgc ccccacacca agctcgcgcg ccccggctct gtctcccacc cggcctccta aaaagcctct ggactatgtt caagatcatt cttctggtgt tttcaatgag gcctccttgt atcagtcctc tatagacaga agcctggaaa gacccatgag ttctgcaagc atggccagtg acttcaggaa gcggaggaag agcgagcctg cagtgggtcc accacggggc ttgggagatc aaagtgcgag caggactagc ccaggccgag tggacctccc aggatcaagc accactctta caaagtcttt cactagctct tctccttctt ccccatcaag agcaaaagac cgtgagtccc ctagaagtta ctcatccact ttgactgaca tggggagaag tgcaccaagg gaaagaagag gaactccaga aaaagagaaa ttgcctgcaa aagctgttta tgattttaag gctcagacat ctaaggagtt gtcatttaag aaaggagata ctgtctacat cctcaggaaa attgatcaaa attggtatga gggagaacac cacgggagag tgggcatctt cccgatctca tacgtagaga aactcacacc tcctgagaaa gcacagcctg caagaccacc tccgccagcc cagcccggag aaatcggaga agctatagcc aaatacaact tcaacgcaga cacaaatgtg gagctgtcac tgagaaaggg agatagagtt attcttctta aaagagttga tcaaaactgg tatgaaggta aaatcccagg aaccaacaga caaggcatct tccctgtttc ctatgtggag gtcgtcaaga agaacacaaa aggtgctgag gactaccctg accctccaat accccacagc tattctagtg ataggattca cagcttgagc tcaaataagc cacagcgtcc tgtgtttact catgaaaata ttcaaggtgg gggggaaccg tttcaggctc tgtataacta tactcccagg aatgaagatg agctggagct cagagaaagt gatgtcattg atgtcatgga aaagtgtgat gacggctggt ttgtggggac ctcaagaaga accaaattct ttggtacttt ccccggaaac tacgtcaaga ggctgtga
OMIM
616349
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of SORBS2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SORBS2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
80,966 Da
NCBI Official Full Name
Homo sapiens sorbin and SH3 domain containing 2, mRNA
NCBI Official Synonym Full Names
sorbin and SH3 domain containing 2
NCBI Official Symbol
SORBS2  [Similar Products]
NCBI Official Synonym Symbols
ARGBP2; PRO0618
  [Similar Products]
NCBI Protein Information
sorbin and SH3 domain-containing protein 2
UniProt Protein Name
Sorbin and SH3 domain-containing protein 2
UniProt Synonym Protein Names
Arg-binding protein 2; ArgBP2; Arg/Abl-interacting protein 2; Sorbin
UniProt Gene Name
SORBS2  [Similar Products]
UniProt Synonym Gene Names
ARGBP2; KIAA0777; ArgBP2  [Similar Products]
UniProt Entry Name
SRBS2_HUMAN
NCBI Summary for SORBS2
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for SORBS2
ArgBP2: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q35.1

Cellular Component: actin cytoskeleton

Molecular Function: cytoskeletal adaptor activity; protein binding; structural constituent of cytoskeleton; structural constituent of muscle
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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