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Sox2 recombinant protein

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Catalog # MBS539581
Unit / Price
  0.025 mg  /  $310 +1 FREE 8GB USB
Sox2 recombinant protein
Product Name

Sox2, Recombinant Protein

Popular Item
Also Known As

Sox2 protein

Product Synonym Names
Sox-2; Sox-2 protein; Sox 2 protein; Sex Determining Region Y- box 2 protein; Sox2; Sox 2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
199
Sequence
Region of Sox2 protein correspond ing to amino acids MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHM.
Host
E.coli
Purity/Purification
> 95% by SDS-PAGE and HPLC analysis.
Form/Format
Lyophilized from 10mM Sodium Acetate, pH 6.0 0.2u sterile filtered.
Concentration
25ug/vial;lyophilized (lot specific)
Grade
Recombinant Protein
Contaminants
Endotoxin level less than 0.1ng per ug
Protein Type
Recombinant
Biological Significance
Sox2, also known as sex determining region Y (SRY)-box 2, belongs to a diverse family of structurally-related transcription factors whose primary structure contains a 79-residue DNA-binding domain, called high mobility group (HMG) box. It plays an essential role in maintaining the pluripotency of embryonic stem cells (ESC) and determination of cell fate. Microarray analysis showed that Sox2 regulates the expression of multiple genes involved in embryonic development including FGF4, YES1 and ZFP206. Sox2 acts as a transcriptional activator after forming a ternary complex with Oct3/4 and a conserved non-coding DNA sequence (CNS1) located approximately 2 kb upstream of the RAX promoter. The introduction of Sox2, Oct4, Myc, and Klf4, into human dermal fibroblasts isolated from a skin biopsy of a healthy research fellow was sufficient to confer a pluripotent state upon the fibroblast genome.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Biohazard
Not for human use, use normal laboratory precautions when handling reagent. For research purposes only.
Preparation and Storage
Ships ambient or refrigerated. Upon receipt store at -20 degree C. After reconstituted, can be stored at 4 degree C fo rup to 1 week. Working aliquots stored with a carrier protein are stable for at least 3 months at -20 degree C.
Other Notes
Small volumes of Sox2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Sox2 recombinant protein
Purified recombinant Human Sox2 protein
Product Categories/Family for Sox2 recombinant protein
Applications Tested/Suitable for Sox2 recombinant protein
User optimized
NCBI/Uniprot data below describe general gene information for Sox2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
Molecular Weight
34.3 kDa
NCBI Official Full Name
Sox2, partial
UniProt Protein Name
Sox2
UniProt Synonym Protein Names
Sox2
UniProt Gene Name
UniProt Entry Name
A4GU07_OREMO
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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