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SREBP elisa kit :: Hamster Sterol Regulatory Element Binding Proteins ELISA Kit

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Catalog # MBS013430
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SREBP elisa kit
Product Name

Sterol Regulatory Element Binding Proteins (SREBP), ELISA Kit

Full Product Name

Hamster Sterol Regulatory Element Binding Proteins ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
600481
3D Structure
ModBase 3D Structure for Q12772
Species Reactivity
Assay Type
Sandwich
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of SREBP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for SREBPpurchase
MBS013430 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Sterol Regulatory Element Binding Proteins (SREBP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SREBP. The ELISA analytical biochemical technique of the MBS013430 kit is based on SREBP antibody-SREBP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SREBP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SREBP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for SREBP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
123,688 Da
NCBI Official Full Name
sterol regulatory element binding protein-2
NCBI Official Synonym Full Names
sterol regulatory element binding transcription factor 2
NCBI Official Symbol
SREBF2  [Similar Products]
NCBI Official Synonym Symbols
SREBP2; bHLHd2; SREBP-2
  [Similar Products]
NCBI Protein Information
sterol regulatory element-binding protein 2; class D basic helix-loop-helix protein 2; sterol regulatory element-binding transcription factor 2
UniProt Protein Name
Sterol regulatory element-binding protein 2
UniProt Synonym Protein Names
Class D basic helix-loop-helix protein 2; bHLHd2; Sterol regulatory element-binding transcription factor 2
UniProt Gene Name
SREBF2  [Similar Products]
UniProt Synonym Gene Names
BHLHD2; SREBP2; SREBP-2; bHLHd2  [Similar Products]
UniProt Entry Name
SRBP2_HUMAN
NCBI Summary for SREBP
This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
UniProt Comments for SREBP
SREBP-2: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway. Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes. Belongs to the SREBP family.

Protein type: Membrane protein, multi-pass; Transcription factor; DNA-binding; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q13

Cellular Component: nucleoplasm; Golgi membrane; endoplasmic reticulum membrane; endoplasmic reticulum; cytoplasm; nucleolus; nucleus; cytosol

Molecular Function: protein C-terminus binding; protein dimerization activity; protein binding; C-8 sterol isomerase activity

Biological Process: cholesterol metabolic process; transcription, DNA-dependent; response to low density lipoprotein stimulus; positive regulation of transcription from RNA polymerase II promoter; cellular lipid metabolic process; negative regulation of transcription from RNA polymerase II promoter; lipid metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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