NP_001166031.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,202 Da
NCBI Official Full Name
somatostatin receptor type 5
NCBI Official Synonym Full Names
somatostatin receptor 5
NCBI Official Synonym Symbols
NCBI Protein Information
somatostatin receptor type 5; somatostatin receptor subtype 5
UniProt Protein Name
Somatostatin receptor type 5
UniProt Synonym Gene Names
UniProt Entry Name
SSR5_HUMAN
NCBI Summary for SSTR5
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010]
UniProt Comments for SSTR5
SSTR5: Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Cell cycle regulation; Receptor, GPCR
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: neuron projection; integral to plasma membrane; plasma membrane
Molecular Function: neuropeptide binding; somatostatin receptor activity
Biological Process: positive regulation of cytokinesis; synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; negative regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; glucose homeostasis; regulation of insulin secretion
Disease: Pituitary Adenoma, Growth Hormone-secreting
Research Articles on SSTR5
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Products associated with SSTR5 elisa kit
Pathways associated with SSTR5 elisa kit
Diseases associated with SSTR5 elisa kit
Organs/Tissues associated with SSTR5 elisa kit
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