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anti-STAG3 antibody :: Rabbit anti-Human STAG3 Antibody

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Catalog # MBS000003
Unit / Price
  0.05 mL  /  $270 +1 FREE 8GB USB
  0.1 mL  /  $445 +1 FREE 8GB USB
anti-STAG3 antibody
Product Name

STAG3, Antibody

Popular Item
Also Known As

Rabbit STAG3 Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1225
Chromosome Location
Chromosome: 7; NC_000007.13 (99775538..99812010). Location: 7q22.1
OMIM
608489
3D Structure
ModBase 3D Structure for Q9UJ98
Host
Rabbit
Species Reactivity
Human
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Other Notes
Small volumes of anti-STAG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-STAG3 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for STAG3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
139,034 Da
NCBI Official Full Name
cohesin subunit SA-3
NCBI Official Synonym Full Names
stromal antigen 3
NCBI Official Symbol
STAG3  [Similar Products]
NCBI Protein Information
cohesin subunit SA-3; stromalin 3; stromalin-3; SCC3 homolog 3
UniProt Protein Name
Cohesin subunit SA-3
UniProt Synonym Protein Names
SCC3 homolog 3; Stromal antigen 3; Stromalin-3
Protein Family
UniProt Gene Name
STAG3  [Similar Products]
UniProt Entry Name
STAG3_HUMAN
NCBI Summary for STAG3
The protein encoded by this gene is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Apr 2014]
UniProt Comments for STAG3
STAG3: Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis- specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I. Belongs to the SCC3 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: extracellular space; nucleolus; synaptonemal complex; nucleus; chromosome, pericentric region

Biological Process: synaptonemal complex assembly

Disease: Premature Ovarian Failure 8
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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