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STIP1 cdna clone

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Catalog # MBS1272398
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
STIP1 cdna clone
Product Name

STIP1, cDNA Clone

Popular Item
Full Product Name

STIP1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggagcagg tcaatgagct gaaggagaaa ggcaacaagg ccctgagcgt gggtaacatc gatgatgcct tacagtgcta ctccgaagct attaagctgg atccccacaa ccacgtgctg tacagcaacc gttctgctgc ctatgccaag aaaggagact accagaaggc ttatgaggat ggctgcaaga ctgtcgacct aaagcctgac tggggcaagg gctattcacg aaaagcagca gctctagagt tcttaaaccg ctttgaagaa gccaagcgaa cctatgagga gggcttaaaa cacgaggcaa ataaccctca actgaaagag ggtttacaga atatggaggc caggttggca gagagaaaat tcatgaaccc tttcaacatg cctaatctgt atcagaagtt ggagagtgat cccaggacaa ggacactact cagtgatcct acctaccggg agctgataga gcagctacga aacaagcctt ctgacctggg cacgaaacta caagatcccc ggatcatgac cactctcagc gtcctccttg gggtcgatct gggcagtatg gatgaggagg aagagattgc aacacctcca ccaccacccc ctcccaaaaa ggagaccaag ccagagccaa tggaagaaga tcttccagag aataagaagc aggcactgaa agaaaaagag ctggggaacg atgcctacaa gaagaaagac tttgacacag ccttgaagca ttacgacaaa gccaaggagc tggaccccac taacatgact tacattacca atcaagcagc ggtatacttt gaaaagggcg actacaataa gtgccgggag ctttgtgaga aggccattga agtggggaga gaaaaccgag aagactatcg acagattgcc aaagcatatg ctcgaattgg caactcctac ttcaaagaag aaaagtacaa ggatgccatc catttctata acaagtctct ggcagagcac cgaaccccag atgtgctcaa gaaatgccag caggcagaga aaatcctgaa ggagcaagag cggctggcct acataaaccc cgacctggct ttggaggaga agaacaaagg caacgagtgt tttcagaaag gggactatcc ccaggccatg aagcattata cagaagccat caaaaggaac ccgaaagatg ccaaattata cagcaatcga gctgcctgct acaccaaact cctggagttc cagctggcac tcaaggactg tgaggaatgt atccagctgg agccgacctt catcaagggt tatacacgga aagccgctgc gctggaagcg atgaaggact acaccaaagc catggatgtg taccagaagg cgctagacct ggactccagc tgtaaggagg cggcagacgg ctaccagcgc tgtatgatgg cgcagtacaa ccggcacgac agccccgaag atgtgaagcg acgagccatg gccgaccctg aggtgcagca gatcatgagt gacccagcca tgcgccttat cctggaacag atgcagaagg acccccaggc actcagcgaa cacttaaaga atcctgtaat agcacagaag atccagaagc tgatggatgt gggtctgatt gcaattcggt ga
OMIM
605063
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of STIP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for STIP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
59,778 Da
NCBI Official Full Name
Homo sapiens stress-induced-phosphoprotein 1, mRNA
NCBI Official Synonym Full Names
stress induced phosphoprotein 1
NCBI Official Symbol
STIP1  [Similar Products]
NCBI Official Synonym Symbols
HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521
  [Similar Products]
NCBI Protein Information
stress-induced-phosphoprotein 1
UniProt Protein Name
Stress-induced-phosphoprotein 1
UniProt Synonym Protein Names
Hsc70/Hsp90-organizing protein; Hop; Renal carcinoma antigen NY-REN-11; Transformation-sensitive protein IEF SSP 3521
UniProt Gene Name
STIP1  [Similar Products]
UniProt Synonym Gene Names
STI1; Hop  [Similar Products]
UniProt Entry Name
STIP1_HUMAN
NCBI Summary for STIP1
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]
UniProt Comments for STIP1
STI1: a protein that is apparently involved in the response to stress. Specifically interacts with the C-terminal tails of Hsp70 and Hsp90 via TPR1 and TPR2A domains. Deletion of STI1 reduces the activity of the glucocorticoid receptor, a Hsp90 target protein. Phosphorylated in vitro by p90RSK and casein kinase II.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: Golgi apparatus; nucleus

Molecular Function: protein binding

Biological Process: response to stress
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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