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STX12 recombinant protein

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Catalog # MBS204335
Unit / Price
  0.02 mg  /  $310 +1 FREE 8GB USB
  0.1 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

STX12, Recombinant Protein

Also Known As

STX12, 1-248aa, Human, His tag, E Coli

Product Synonym Names
Syntaxin 12; STX13; STX14
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
276
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMSYGPL DMYRNPGPSG PQLRDFSSII QTCSGNIQRI SQATAQIKNL MSQLGTKQDS SKLQENLQQL QHSTNQLAKE TNELLKELGS LPLPLSTSEQ RQQRLQKERL MNDFSAALNN FQAVQRRVSE KEKESIARAR AGSRLSAEER QREEQLVSFD SHEEWNQMQS QEDEVAITEQ DLELIKERET AIRQLEADIL DVNQIFKDLA MMIHDQGDLI DSIEANVESS EVHVERATEQ LQRAAYYQKK SR
OMIM
AF123769 mRNA
3D Structure
ModBase 3D Structure for Q86Y82
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 1mM DTT
Concentration
0.5 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of STX12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
STX12 recombinant protein
Syntaxin 12, also known as, belongs to the syntaxin family. Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. STX12 regulates protein transport between late endosomes and the trans-Golgi network and interacts with ABC1 (ATP-binding cassette transporter A1), a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I (apolipoprotein A-I). Recombinant human STX12 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for STX12 recombinant protein
Applications Tested/Suitable for STX12 recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for STX12. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31.0 kDa (272aa), confirmed by MALDI-TOF
NCBI Official Full Name
syntaxin-12
NCBI Official Synonym Full Names
syntaxin 12
NCBI Official Symbol
STX12  [Similar Products]
NCBI Official Synonym Symbols
STX13; STX14
  [Similar Products]
NCBI Protein Information
syntaxin-12
UniProt Protein Name
Syntaxin-12
Protein Family
UniProt Gene Name
STX12  [Similar Products]
UniProt Comments for STX12
SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting ().
Product References and Citations for STX12 recombinant protein
Tang B L., et al. (1998) J Biol Chem. 273:6944-6950.; Prekeris R., et al. (1998) J Cell Biol. 143: 957-971.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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