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STX1A recombinant protein :: Syntaxin 1A Recombinant Protein

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Catalog # MBS203020
Unit / Price
  0.1 mg  /  $310 +1 FREE 8GB USB
  0.5 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

Syntaxin 1A (STX1A), Recombinant Protein

Popular Item
Full Product Name

Syntaxin 1A, 1-226aa, Human, E Coli

Product Synonym Names
STX1A; STX1; Syntaxin 1A; Neuron-specific antigen HPC-1; Syntaxin-1A; HPC 1; Neuron specific antigen HPC1; STX1; Syntaxin 1A brain.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MKDRTQELRT AKDSDDDDDV AVTVDRDRFM DEFFEQVEEI RGFIDKIAEN VEEVKRKHSA ILASPNPDEK TKEELEELMS DIKKTANKVR SKLKSIEQSI EQEEGLNRSS ADLRIRKTQH STLSRKFVEV MSEYNATQSD YRERCKGRIQ RQLEITGRTT TSEELEDMLE SGNPAIFASG IIMDSSISKQ ALSEIETRHS EIIKLENSIR ELHDMFMDMA MLVESQ
OMIM
L37792 mRNA
3D Structure
ModBase 3D Structure for Q16623
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
In 20mM Tris (pH 7.5), 1mM DTT, 10% glycerol
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of STX1A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
STX1A recombinant protein
Syntaxin is membrane integrated Q-SNARE protein participating in exocytosis. Syntaxin is composed of an N-terminal regulatory domain (Habc), a SNARE domain (known as H3), and a single C-terminal transmembrane domain. The SNARE (H3) domain binds to both synaptobrevin and SNAP-25 forming the core SNARE complex. Recombinant syntaxin 1A protein (1-226aa) contains N-terminal domain (Habc) and t_SNARE domain (H3 domain) and this protein was overexpressed in E Coli and purified by using the conventional column chromatography techniques.
Product Categories/Family for STX1A recombinant protein
Applications Tested/Suitable for STX1A recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for STX1A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26.1 kDa (226 aa), confirmed by MALDI-TOF. [Similar Products]
NCBI Official Full Name
syntaxin-1A isoform 1
NCBI Official Synonym Full Names
syntaxin 1A
NCBI Official Symbol
STX1A  [Similar Products]
NCBI Official Synonym Symbols
STX1; HPC-1; P35-1; SYN1A
  [Similar Products]
NCBI Protein Information
syntaxin-1A
UniProt Protein Name
Syntaxin-1A
UniProt Synonym Protein Names
Neuron-specific antigen HPC-1
Protein Family
UniProt Gene Name
STX1A  [Similar Products]
UniProt Synonym Gene Names
NCBI Summary for STX1A
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
UniProt Comments for STX1A
Plays a role in hormone and neurotransmitter exocytosis (). Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm.
Product References and Citations for STX1A recombinant protein
Han X., et al. (2004) Science. 304:289-292; Woodbury DJ. et al. (2000) Cell Biology International. 24 (11):809-818.;

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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