• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SuMO-1 recombinant protein

Scan QR to view Datasheet
Catalog # MBS203215
Unit / Price
  0.1 mg  /  $290 +1 FREE 8GB USB
  0.5 mg  /  $650 +1 FREE 8GB USB
SDS-Page
Product Name

SuMO-1, Recombinant Protein

Full Product Name

SuMO-1, 1-97aa, Human, E Coli

Product Synonym Names
SMT3 suppressor of mif two 3 homolog 1 isoform a; SMT3 suppressor of mif two 3 homolog 1 isoform a; DAP-1; GMP1; OFC10; PIC1; SENP2; SMT3; SMT3C; SMT3H3; uBL1; SMT3 suppressor of mif two 3 homolog 1 isoform a GAP modifying protein 1; GMP 1; PIC 1; Sentrin; Sentrin 1; Small ubiquitin related modifier 1; SMT3 homolog 3; uBL 1; SMT3 suppressor of mif two 3 homolog 1; Sumo1; ubiquitin homology domain protein PIC1; ubiquitin Like 1; ubiquitin like protein SMT3C; ubiquitin like protein uBL1.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MSDQEAKPST EDLGDKKEGE YIKLKVIGQD SSEIHFKVKM TTHLKKLKES YCQRQGVPMN SLRFLFEGQR IADNHTPKEL GMEEEDVIEV YQEQTGG
OMIM
X99586 mRNA
3D Structure
ModBase 3D Structure for P63165
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of SuMO-1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SuMO-1 recombinant protein
SuMO-1, also known as small ubiquitin-related modifier 1, is a member of the SuMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SuMO-1 protein participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. Recombinant human SuMO1 protein was expressed in E Coli and purified by using conventional chromatography.
Product Categories/Family for SuMO-1 recombinant protein
Applications Tested/Suitable for SuMO-1 recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for SuMO-1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11.1 kDa (97aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
NCBI Official Full Name
small ubiquitin-related modifier 1 isoform a
NCBI Official Synonym Full Names
small ubiquitin-like modifier 1
NCBI Official Symbol
SUMO1  [Similar Products]
NCBI Official Synonym Symbols
DAP1; GMP1; PIC1; SMT3; UBL1; OFC10; SENP2; SMT3C; SMT3H3
  [Similar Products]
NCBI Protein Information
small ubiquitin-related modifier 1
UniProt Protein Name
Small ubiquitin-related modifier 1
UniProt Synonym Protein Names
GAP-modifying protein 1; GMP1; SMT3 homolog 3; Sentrin; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Smt3C; Ubiquitin-like protein UBL1
UniProt Gene Name
SUMO1  [Similar Products]
UniProt Synonym Gene Names
SMT3C; SMT3H3; UBL1; SUMO-1; GMP1; Smt3C  [Similar Products]
NCBI Summary for SuMO-1
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
UniProt Comments for SuMO-1
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1 (PubMed:19223394). Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development. Covalently attached to ZFHX3 (PubMed:24651376).
Product References and Citations for SuMO-1 recombinant protein
Evdokimov E., et al. (2008), J Cell Sci, 121:4106-13.; Hecker CM., et al. (2006). J Biol Chem. 281 (23):16117-27.;

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000