AAH95527.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
52,202 Da
NCBI Official Full Name
TACR3 protein, partial
NCBI Official Synonym Full Names
tachykinin receptor 3
NCBI Protein Information
neuromedin-K receptor; NK-3 receptor; neurokinin B receptor; neurokinin beta receptor
UniProt Protein Name
Neuromedin-K receptor
UniProt Synonym Protein Names
NK-3 receptor; NK-3R; Neurokinin B receptor; Tachykinin receptor 3
UniProt Synonym Gene Names
UniProt Entry Name
NK3R_HUMAN
NCBI Summary for TACR3
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008]
UniProt Comments for TACR3
TACR3: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 4q25
Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; nucleus
Molecular Function: protein binding; tachykinin receptor activity
Biological Process: tachykinin signaling pathway; hyperosmotic salinity response; regulation of dopamine metabolic process; response to morphine; positive regulation of heart rate; response to cocaine; positive regulation of blood pressure; response to estradiol stimulus; aging
Disease: Hypogonadotropic Hypogonadism 11 With Or Without Anosmia
Research Articles on TACR3
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Products associated with TACR3 elisa kit
Pathways associated with TACR3 elisa kit
Diseases associated with TACR3 elisa kit
Organs/Tissues associated with TACR3 elisa kit
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