View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List TCN2 elisa kit :: Bovine transcobalamin II; macrocytic anemia ELISA Kit Catalog # MBS900440 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name transcobalamin II; macrocytic anemia (TCN2), ELISA Kit Full Product Name Bovine Transcobalamin-2, TCN2 ELISA Kit Product Synonym Names Bovine Transcobalamin-2 (TCN2) ELISA kit; D22S676; D22S750; TC2; transcobalamin II; transcobalamin II; macrocytic anemia Product Gene Name TCN2 elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual 3D Structure ModBase 3D Structure for Q9XSC9 Species Reactivity Bovine Specificity This assay has high sensitivity and excellent specificity for detection of Bovine TCN2. No significant cross-reactivity or interference between Bovine TCN2 and analogues was observed. Assay Type Sandwich Intra-assay Precision Intra-assay Precision (Precision within an assay): CV% is less than 8%Three samples of known concentration were tested twenty times on one plate to assess.Inter-assay Precision (Precision between assays): CV% is less than 10%Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength 450 nm Sample Volume 50-100ul Protein Biological Process 1 Transport Protein Biological Process 2 Anion transport Protein Biological Process 3 Cobalt transport Preparation and Storage Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of TCN2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for TCN2 purchase MBS900440 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the transcobalamin II; macrocytic anemia (TCN2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TCN2. The ELISA analytical biochemical technique of the MBS900440 kit is based on TCN2 antibody-TCN2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TCN2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TCN2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for TCN2 elisa kit For the quantitative determination of bovine transcobalamin-2 (TCN2) concentrations in serum, plasma, tissue homogenates. PRINCIPLE This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TCN2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TCN2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TCN2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TCN2 bound in the initial step. The color development is stopped and the intensity of the color is measured. NCBI/Uniprot data below describe general gene information for TCN2. It may not necessarily be applicable to this product. NCBI GI # 99028973 NCBI GeneID 281518 NCBI Accession # NP_776620.2 [Other Products] NCBI GenBank Nucleotide # NM_174195.3 [Other Products] UniProt Primary Accession # Q9XSC9 [Other Products] UniProt Secondary Accession # Q0V8P0; Q1RMV8; Q58CR7; Q58DL8; Q9TR25[Other Products] UniProt Related Accession # Q9XSC9[Other Products] Molecular Weight 47,958 Da TOP NCBI Official Full Name transcobalamin-2 NCBI Official Synonym Full Names transcobalamin II NCBI Official Symbol TCN2 [Similar Products] NCBI Protein Information transcobalamin-2; TC-2; TCII; TC II; transcobalamin II; macrocytic anemia UniProt Protein Name Transcobalamin-2 UniProt Synonym Protein Names Transcobalamin II; TC II; TCII Protein Family Transcobalamin UniProt Gene Name TCN2 [Similar Products] UniProt Synonym Gene Names TC-2; TC II; TCII [Similar Products] UniProt Entry Name TCO2_BOVIN TOP TOP UniProt Comments for TCN2 Function: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. Research Articles on TCN2 1. study investigated crystallographically the beta-ligand exchange on Cbl bound to transcobalamin (TC) by crystallization of bovine holo-TC in the presence of either cyanide or sulfite TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with TCN2 elisa kit Reference Product PubMed Publications MTR elisa kit >20 publications with TCN2 and MTR CD320 elisa kit >4 publications with TCN2 and CD320 CBL elisa kit >3 publications with TCN2 and CBL Pathways associated with TCN2 elisa kit Products by Pathway Pathway Diagram Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway antibodies Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway Diagram Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram Defective BTD Causes Biotidinase Deficiency Pathway antibodies Defective BTD Causes Biotidinase Deficiency Pathway Diagram Defective CD320 Causes Methylmalonic Aciduria Pathway antibodies Defective CD320 Causes Methylmalonic Aciduria Pathway Diagram Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram Defective GIF Causes Intrinsic Factor Deficiency Pathway antibodies Defective GIF Causes Intrinsic Factor Deficiency Pathway Diagram Defective HLCS Causes Multiple Carboxylase Deficiency Pathway antibodies Defective HLCS Causes Multiple Carboxylase Deficiency Pathway Diagram Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway antibodies Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway Diagram Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway antibodies Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway Diagram Defective MMAB Causes Methylmalonic Aciduria Type CblB Pathway antibodies Defective MMAB Causes Methylmalonic Aciduria Type CblB Pathway Diagram Diseases associated with TCN2 elisa kit Disease Name Pubmed Publications TRANSCOBALAMIN II DEFICIENCY Antibodies >12 publications with TCN2 and TRANSCOBALAMIN II DEFICIENCY Nervous System Diseases Antibodies >9 publications with TCN2 and Nervous System Diseases Brain Diseases Antibodies >5 publications with TCN2 and Brain Diseases Vascular Diseases Antibodies >5 publications with TCN2 and Vascular Diseases Anemia Antibodies >5 publications with TCN2 and Anemia Anemia, Megaloblastic Antibodies >5 publications with TCN2 and Anemia, Megaloblastic Cleft Lip Antibodies >4 publications with TCN2 and Cleft Lip Colorectal Neoplasms Antibodies >3 publications with TCN2 and Colorectal Neoplasms Kidney Diseases Antibodies >2 publications with TCN2 and Kidney Diseases Heart Diseases Antibodies >2 publications with TCN2 and Heart Diseases Organs/Tissues associated with TCN2 elisa kit Organ/Tissue Name Pubmed Publications Brain Antibodies >2 publications with TCN2 and Brain Kidney Antibodies >2 publications with TCN2 and Kidney Pancreas Antibodies >1 publications with TCN2 and Pancreas Muscle Antibodies >1 publications with TCN2 and Muscle Intestine Antibodies >1 publications with TCN2 and Intestine TOP © 2006-24 MyBioSource.com. 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