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Tdo2 recombinant protein :: Tryptophan 2,3-dioxygenase Recombinant Protein

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Catalog # MBS958462
Unit / Price
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  0.01 mg (E-Coli)  /  $235 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $320 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $535 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $855 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,125 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
SDS-PAGE
Product Name

Tryptophan 2,3-dioxygenase (Tdo2), Recombinant Protein

Popular Item
Full Product Name

Recombinant Rat Tryptophan 2,3-dioxygenase(Tdo2)

Product Synonym Names
Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; Tryptophan pyrrolase; Tryptophanase
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-406aa; Full Length
Sequence
MSGCPFSGNS VGYTLKNLSM EDNEEDGAQT GVNRASKGGL IYGDYLQLEK ILNAQELQSE IKGNKIHDEH LFIITHQAYE LWFKQILWEL DSVREIFQNG HVRDERNMLK VMTRMHRVVV IFKLLVQQFS VLETMTALDF NDFREYLSPA SGFQSLQFRL LENKIGVLQS LRVPYNRKHY RDNFEGDYNE LLLKSEQEQT LLQLVEAWLE RTPGLEPHGF NFWGKFEKNI LKGLEEEFLK IQAKKDSEEK EEQMAEFRKQ KEVLLCLFDE KRHDYLLSKG ERRLSYRALQ GALMIYFYRE EPRFQVPFQL LTSLMDIDTL MTKWRYNHVC MVHRMLGSKA GTGGSSGYYY LRSTVSDRYK VFVDLFNLSS YLVPRHWIPK MNPIIHKFLY TAEYSDSSYF SSDESD
3D Structure
ModBase 3D Structure for P21643
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rat
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Tdo2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Tdo2 recombinant protein
Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin.
Product Categories/Family for Tdo2 recombinant protein

Tdo2 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Tdo2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
60.66kD
NCBI Official Full Name
tryptophan 2,3-dioxygenase
NCBI Official Synonym Full Names
tryptophan 2,3-dioxygenase
NCBI Official Symbol
NCBI Official Synonym Symbols
TO; Tdo
  [Similar Products]
NCBI Protein Information
tryptophan 2,3-dioxygenase
UniProt Protein Name
Tryptophan 2,3-dioxygenase
UniProt Synonym Protein Names
Tryptamin 2,3-dioxygenase
UniProt Gene Name
UniProt Synonym Gene Names
Tdo; TDO; TO; TRPO  [Similar Products]
UniProt Entry Name
T23O_RAT
NCBI Summary for Tdo2
rate-limiting enzyme in the catabolism of tryptophan [RGD, Feb 2006]
UniProt Comments for Tdo2
TDO2: Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin. Belongs to the tryptophan 2,3-dioxygenase family.

Protein type: Amino Acid Metabolism - tryptophan; Oxidoreductase; EC 1.13.11.11

Molecular Function: amino acid binding; heme binding; metal ion binding; oxygen binding; tryptophan 2,3-dioxygenase activity

Biological Process: tryptophan catabolic process to acetyl-CoA; tryptophan catabolic process to kynurenine; tryptophan metabolic process
Product References and Citations for Tdo2 recombinant protein
"Nucleotide sequence of a fragment of the rat tryptophan oxygenase gene showing high affinity to glucocorticoid receptor in vitro." Merkulov V.M., Merkulova T.I. Biochim. Biophys. Acta 1132:100-102(1992)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with Tdo2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >8 publications with Tdo2 and Liver
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