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TFRC blocking peptide :: CD71 Blocking Peptide

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Catalog # MBS823885
Unit / Price
  1 mg  /  $160 +1 FREE 8GB USB
  5 mg  /  $305 +1 FREE 8GB USB
TFRC blocking peptide
Product Name

CD71 (TFRC), Blocking Peptide

Popular Item
Full Product Name

CD71 Blocking Peptide

Product Synonym Names
Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; T9; p90; CD71
Antibody/Peptide Pairs
CD71 peptide (MBS823885) is used for blocking the activity of CD71 antibody (MBS822109)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
190010
3D Structure
ModBase 3D Structure for P02786
Host
Synthetic
Species Reactivity
Human, Mouse, Chicken, Dog, Pig
Purity/Purification
>85%
Form/Format
Lyophilized powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4°C. Store at -20°C for one year.
Other Notes
Small volumes of TFRC blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
TFRC blocking peptide
The peptide is used to block Anti-CD71 Antibody reactivity.
Applications Tested/Suitable for TFRC blocking peptide
Blocking (BL)
Application Notes for TFRC blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4°C for overnight or at room temperature for 2 hours.
NCBI/Uniprot data below describe general gene information for TFRC. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
transferrin receptor protein 1
NCBI Official Synonym Full Names
transferrin receptor
NCBI Official Symbol
NCBI Official Synonym Symbols
T9; TR; TFR; p90; CD71; TFR1; TRFR
  [Similar Products]
NCBI Protein Information
transferrin receptor protein 1; transferrin receptor (p90, CD71)
UniProt Protein Name
Transferrin receptor protein 1
UniProt Synonym Protein Names
T9; p90; CD_antigen: CD71Cleaved into the following chain:Transferrin receptor protein 1, serum form; sTfR
UniProt Gene Name
UniProt Synonym Gene Names
TR; TfR; TfR1; Trfr; sTfR  [Similar Products]
UniProt Entry Name
TFR1_HUMAN
UniProt Comments for TFRC
TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system.

Protein type: Membrane protein, integral; Cell surface; Receptor, misc.

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; integral to plasma membrane; cytoplasmic membrane-bound vesicle; extracellular region; coated pit; recycling endosome; membrane; perinuclear region of cytoplasm; melanosome; plasma membrane; vesicle; endosome; external side of plasma membrane

Molecular Function: identical protein binding; protein binding; transferrin receptor activity; double-stranded RNA binding

Biological Process: receptor-mediated endocytosis; viral reproduction; cellular iron ion homeostasis; positive regulation of bone resorption; transferrin transport; osteoclast differentiation; regulation of cell growth; transmembrane transport; regulation of cell proliferation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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