NP_035768.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
85,731 Da
NCBI Official Full Name
transferrin receptor protein 1
NCBI Official Synonym Full Names
transferrin receptor
NCBI Official Synonym Symbols
TR; TFR; p90; CD71; TFR1; Trfr; Mtvr1; Mtvr-1; AI195355; AI426448; AU015758; 2610028K12Rik; E430033M20Rik [Similar Products]
NCBI Protein Information
transferrin receptor protein 1; mammary tumor virus receptor 1
UniProt Protein Name
Transferrin receptor protein 1
UniProt Synonym Protein Names
CD_antigen: CD71
UniProt Synonym Gene Names
UniProt Entry Name
TFR1_MOUSE
NCBI Summary for TFRC
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis. [provided by RefSeq, Mar 2010]
UniProt Comments for TFRC
Function: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system 1 PublicationManual assertion based on experiment in:Ref.5
Research Articles on TFRC
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Products associated with TFRC elisa kit
Pathways associated with TFRC elisa kit
Diseases associated with TFRC elisa kit
Organs/Tissues associated with TFRC elisa kit
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