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Thoc1 recombinant protein :: THO complex subunit 1 (Thoc1) Recombinant Protein

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Catalog # MBS965665
Unit / Price
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  0.05 mg (E-Coli)  /  $750 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $850 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,005 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,080 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,110 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,150 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,305 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,320 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,565 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,675 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,035 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,070 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,145 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,150 +3 FREE 8GB USB
Thoc1 recombinant protein
Product Name

THO complex subunit 1 (Thoc1), Recombinant Protein

Full Product Name

Recombinant Rat THO complex subunit 1 (Thoc1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-343aa, Full length protein
Sequence
MEYYSAIKNN DIMKFLSKWM GVEEIIPKAG KEPDVLQQTM DTENVVYLHN GLLLSYNDFM KFIGKWMELE YIILSEFCEE RASYTKLKRG VWKRSAPEDF LDKRPNKKIL IGNEELTRLW NLCPDNMEAC KLETREYMPI LEEFFEEAIE QADAENMVES EYKAINNSNY GWSTLRFLAW RSPHFFQPTN QQFKNMTEYL ENMVIKLAKE LPPHSEEIKT GEDEDEEDND ALLKENESPD VRQDKPITGE RIESLTNKLD EQWKILAPYL EIKDSDIRQI ECYSEDMKKR AKQLLVAWKD QEGVHETTDN LIGALNKSGL SDLAESLTND TETNSYLLSL LFY
3D Structure
ModBase 3D Structure for P59924
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rat
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Thoc1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Thoc1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
40,243 Da
NCBI Official Full Name
THO complex subunit 1
NCBI Official Synonym Full Names
uncharacterized LOC302729
NCBI Official Symbol
Da2-19  [Similar Products]
UniProt Protein Name
THO complex subunit 1
UniProt Synonym Protein Names
Liver regeneration-related protein LRRG175; Nuclear matrix protein p84
UniProt Gene Name
Thoc1  [Similar Products]
UniProt Synonym Gene Names
UniProt Comments for Thoc1
Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. Regulates transcriptional elongation of a subset of genes. Involved in genome stability by preventing co-transcriptional R-loop formation ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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