DAA12830.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,032 Da
NCBI Official Full Name
TPA: metalloproteinase inhibitor 1
NCBI Official Synonym Full Names
TIMP metallopeptidase inhibitor 1
NCBI Protein Information
metalloproteinase inhibitor 1
UniProt Protein Name
Metalloproteinase inhibitor 1
UniProt Synonym Protein Names
Embryogenin-1; EG-1; Tissue inhibitor of metalloproteinases 1; TIMP-1
UniProt Synonym Gene Names
UniProt Comments for TIMP-1
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.
Research Articles on TIMP-1
Precautions
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Disclaimer
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Products associated with TIMP-1 elisa kit
Pathways associated with TIMP-1 elisa kit
Diseases associated with TIMP-1 elisa kit
Organs/Tissues associated with TIMP-1 elisa kit
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