NP_003247.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,503 Da
NCBI Official Full Name
metalloproteinase inhibitor 4
NCBI Official Synonym Full Names
TIMP metallopeptidase inhibitor 4
NCBI Official Synonym Symbols
NCBI Protein Information
metalloproteinase inhibitor 4
UniProt Protein Name
Metalloproteinase inhibitor 4
UniProt Synonym Protein Names
Tissue inhibitor of metalloproteinases 4; TIMP-4
UniProt Synonym Gene Names
NCBI Summary for TIMP4
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008]
UniProt Comments for TIMP4
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
Research Articles on TIMP4
Precautions
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Disclaimer
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Products associated with TIMP4 rtu elisa kit
Pathways associated with TIMP4 rtu elisa kit
Diseases associated with TIMP4 rtu elisa kit
Organs/Tissues associated with TIMP4 rtu elisa kit
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