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TLR7 elisa kit :: Human Toll-like receptor 7 ELISA Kit

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Catalog # MBS2883924
Unit / Price
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  48-Strip-Wells  /  $355 +1 FREE 8GB USB
  96-Strip-Wells  /  $475 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,030 +2 FREE 8GB USB
  10x96-Strip-Wells  /  $3,700 +4 FREE 8GB USB
Typical Testing Data/Standard Curve (for reference only)
Product Name

Toll-like receptor 7 (TLR7), ELISA Kit

Popular Item
Full Product Name

Human Toll-like receptor 7 ELISA Kit

Product Synonym Names
Toll-like receptor 7; TLR7; UNQ248/PRO285
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
MBS2883924 Testing Data
OMIM
300365
3D Structure
ModBase 3D Structure for Q9NYK1
Species Reactivity
Specificity
Recombinant and natural Human Toll-like receptor 7 Synonyms: Toll-like receptor 7,;
Samples
serum, plasma, tissue homogenates?cell culture supernates or other biological fluids
Detection Range
0.156-10 ng/mL
Sensitivity
<0.09 ng/mL
Intra-assay Precision
Intra-Assay CV: ?5.2%
Inter-assay Precision
Inter-Assay CV: ?9.9%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of TLR7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forTLR7purchase
MBS2883924 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Toll-like receptor 7 (TLR7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TLR7. The ELISA analytical biochemical technique of the MBS2883924 kit is based on TLR7 antibody-TLR7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TLR7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TLR7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
TLR7 elisa kit
Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates?cell culture supernates or other biological fluids.

Typical Testing Data/Standard Curve (for reference only) of TLR7 elisa kit
TLR7 elisa kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS2883924. Click to request current manual
NCBI/Uniprot data below describe general gene information for TLR7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
120,922 Da
NCBI Official Full Name
toll-like receptor 7
NCBI Official Synonym Full Names
toll like receptor 7
NCBI Official Symbol
NCBI Official Synonym Symbols
TLR7-like
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NCBI Protein Information
toll-like receptor 7
UniProt Protein Name
Toll-like receptor 7
Protein Family
UniProt Gene Name
UniProt Entry Name
TLR7_HUMAN
NCBI Summary for TLR7
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
UniProt Comments for TLR7
TLR7: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Interacts with MYD88 via their respective TIR domains. Interacts with UNC93B1. Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells. Belongs to the Toll-like receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xp22.3

Cellular Component: cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; endosome; endosome membrane; Golgi membrane; integral to membrane; lysosome; plasma membrane; receptor complex

Molecular Function: double-stranded RNA binding; drug binding; single-stranded RNA binding; siRNA binding; transmembrane receptor activity

Biological Process: defense response to virus; I-kappaB phosphorylation; inflammatory response; innate immune response; microglial cell activation; MyD88-dependent toll-like receptor signaling pathway; positive regulation of chemokine production; positive regulation of inflammatory response; positive regulation of interferon-alpha biosynthetic process; positive regulation of interferon-beta biosynthetic process; positive regulation of interferon-gamma biosynthetic process; positive regulation of interleukin-6 production; positive regulation of interleukin-8 biosynthetic process; positive regulation of interleukin-8 production; positive regulation of NF-kappaB import into nucleus; regulation of protein amino acid phosphorylation; toll-like receptor 7 signaling pathway; toll-like receptor 9 signaling pathway; toll-like receptor signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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