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TMEM59 cdna clone

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Catalog # MBS1266626
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
TMEM59 cdna clone
Product Name

TMEM59, cDNA Clone

Popular Item
Full Product Name

TMEM59 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcggcgc cgaaggggag cctctgggtg aggacccaac tggggctccc gccgctgctg ctgctgacca tggccttggc cggaggttcg gggaccgctt cggctgaagc atttgactcg gtcttgggtg atacggcgtc ttgccaccgg gcctgtcagt tgacctaccc cttgcacacc taccctaagg aagaggagtt gtacgcatgt cagagaggtt gcaggctgtt ttcaatttgt cagtttgtgg atgatggaat tgacttaaat cgaactaaat tggaatgtga atctgcatgt acagaagcat attcccaatc tgatgagcaa tatgcttgcc atcttggttg ccagaatcag ctgccattcg ctgaactgag acaagaacaa cttatgtccc tgatgccaaa aatgcaccta ctctttcctc taactctggt gaggtcattc tggagtgaca tgatggactc cgcacagagc ttcataacct cttcatggac tttttatctt caagccgatg acggaaaaat agttatattc cagtctaagc cagaaatcca gtacgcacca catttggagc aggagcctac aaatttgaga gaatcatctc taagcaaaat gtcctcagat ctgcaaatga gaaattcaca agcgcacagg aattttcttg aagatggaga aagtgatggc tttttaagat gcctctctct taactctggg tggattttaa ctacaactct tgtcctctcg gtgatggtat tgctttggat ttgttgtgca actgttgcta cagctgtgga gcagtatgtt ccctctgaga agctgagtat ctatggtgac ttggagttta tgaatgaaca aaagctaaac agatatccag cttcttctct tgtggttgtt agatctaaaa ctgaagatca tgaagaagca gggcctctac ctacaaaagt gaatcttgct cattctgaaa tttaa
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of TMEM59 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TMEM59. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,223 Da
NCBI Official Full Name
Homo sapiens transmembrane protein 59, mRNA
NCBI Official Synonym Full Names
transmembrane protein 59
NCBI Official Symbol
TMEM59  [Similar Products]
NCBI Official Synonym Symbols
DCF1; C1orf8; PRO195; UNQ169; HSPC001
  [Similar Products]
NCBI Protein Information
transmembrane protein 59
UniProt Protein Name
Transmembrane protein 59
UniProt Synonym Protein Names
Liver membrane-bound protein
Protein Family
UniProt Gene Name
TMEM59  [Similar Products]
UniProt Synonym Gene Names
C1orf8  [Similar Products]
UniProt Entry Name
TMM59_HUMAN
NCBI Summary for TMEM59
This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
UniProt Comments for TMEM59
TMEM59: Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding. Belongs to the TMEM59 family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p32.3

Cellular Component: Golgi cis cisterna; Golgi medial cisterna; Golgi trans cisterna; late endosome; lysosome

Molecular Function: protein binding

Biological Process: positive regulation of autophagy
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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