• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

TNFRSF13B recombinant protein

Scan QR to view Datasheet
Catalog # MBS204899
Unit / Price
Scan QR to view Datasheet
  0.1 mg  /  $310 +1 FREE 8GB USB
  0.5 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

TNFRSF13B, Recombinant Protein

Popular Item
Full Product Name

TNFRSF13B, 1-165aa, Human, His tag, E Coli (Denatured)

Product Synonym Names
Tumor necrosis factor receptor superfamily member 13B; CD267; CVID; CVID2; TACI; TNFRSF14B
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSGLGRS RRGGRSRVDQ EERFPQGLWT GVAMRSCPEE QYWDPLLGTC MSCKTICNHQ SQRTCAAFCR SLSCRKEQGK FYDHLLRDCI SCASICGQHP KQCAYFCENK LRSPVNLPPE LRRQRSGEVE NNSDNSGRYQ GLEHRGSEAS PALPGLKLSA DQVALVYS
OMIM
AF023614 mRNA
3D Structure
ModBase 3D Structure for O14836
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol 0.4M urea
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of TNFRSF13B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
TNFRSF13B recombinant protein
TNFRSF13B, also known as TACI, is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). It was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family. It controls T cell-independent B cell antibody responses, isotype switching, and B cell homeostasis. Recombinant human TNFRSF13B protein, fused to His-tag at N-terminus, was expressed in E Coli.
Product Categories/Family for TNFRSF13B recombinant protein
Applications Tested/Suitable for TNFRSF13B recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for TNFRSF13B. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20.9 kDa (188aa)
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 13B
NCBI Official Synonym Full Names
TNF receptor superfamily member 13B
NCBI Official Symbol
TNFRSF13B  [Similar Products]
NCBI Official Synonym Symbols
CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B
  [Similar Products]
NCBI Protein Information
tumor necrosis factor receptor superfamily member 13B
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 13B
UniProt Synonym Protein Names
Transmembrane activator and CAML interactor; CD_antigen: CD267
UniProt Gene Name
TNFRSF13B  [Similar Products]
UniProt Synonym Gene Names
NCBI Summary for TNFRSF13B
The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
UniProt Comments for TNFRSF13B
Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
Product References and Citations for TNFRSF13B recombinant protein
Wu Y. et al. (2000) J Biol Chem. 275:35478-35485.; von Bulow Gu. et al. (1997) Science. 278:138-141.;

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000