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TNFRSF14 cdna clone

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Catalog # MBS1266815
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
TNFRSF14 cdna clone
Product Name

TNFRSF14, cDNA Clone

Popular Item
Also Known As

TNFRSF14 cDNA Clone

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
852
Sequence
atggagcctc ctggagactg ggggcctcct ccctggagat ccacccccag aaccgacgtc ttgaggctgg tgctgtatct caccttcctg ggagccccct gctacgcccc agctctgccg tcctgcaagg aggacgagta cccagtgggc tccgagtgct gccccaagtg cagtccaggt tatcgtgtga aggaggcctg cggggagctg acgggcacag tgtgtgaacc ctgccctcca ggcacctaca ttgcccacct caatggccta agcaagtgtc tgcagtgcca aatgtgtgac ccagccatgg gcctgcgcgc gagccggaac tgctccagga cagagaacgc cgtgtgtggc tgcagcccag gccacttctg catcgtccag gacggggacc actgcgccgc gtgccgcgct tacgccacct ccagcccggg ccagagggtg cagaagggag gcaccgagag tcaggacacc ctgtgtcaga actgcccccc ggggaccttc tctcccaatg ggaccctgga ggaatgtcag caccagacca agtgcagctg gctggtgacg aaggccggag ctgggaccag cagctcccac tgggtatggt ggtttctctc agggagcctc gtcatcgtca ttgtttgctc cacagttggc ctaatcatat gtgtgaaaag aagaaagcca aggggtgatg tagtcaaggt gatcgtctcc gtccagcgga aaagacagga ggcagaaggt gaggccacag tcattgaggc cctgcaggcc cctccggacg tcaccacggt ggccgtggag gagacaatac cctcattcac ggggaggagc ccaaaccact ga
Chromosome Location
Chromosome: 1; NC_000001.10 (2487805..2495268). Location: 1p36.32
OMIM
602746
3D Structure
ModBase 3D Structure for Q92956
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of TNFRSF14 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
TNFRSF14 cdna clone
Homo sapiens tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), mRNA (cDNA clone MGC:3753 IMAGE:3614650), complete cds.
NCBI/Uniprot data below describe general gene information for TNFRSF14. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,392 Da
NCBI Official Full Name
Homo sapiens tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), mRNA
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 14
NCBI Official Symbol
TNFRSF14  [Similar Products]
NCBI Official Synonym Symbols
TR2; ATAR; HVEA; HVEM; CD270; LIGHTR
  [Similar Products]
NCBI Protein Information
tumor necrosis factor receptor superfamily member 14; CD40-like protein; herpesvirus entry mediator A; herpes virus entry mediator A; tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 14
UniProt Synonym Protein Names
Herpes virus entry mediator A; Herpesvirus entry mediator A; HveA; Tumor necrosis factor receptor-like 2
UniProt Gene Name
TNFRSF14  [Similar Products]
UniProt Synonym Gene Names
HVEA; HVEM; Herpesvirus entry mediator A; HveA; TR2  [Similar Products]
UniProt Entry Name
TNR14_HUMAN
NCBI Summary for TNFRSF14
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq, Jul 2008]
UniProt Comments for TNFRSF14
TNFRSF14: Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.

Protein type: Membrane protein, integral; Receptor, misc.; Cell cycle regulation

Chromosomal Location of Human Ortholog: 1p36.32

Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: viral receptor activity; protein binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding

Biological Process: positive regulation of peptidyl-tyrosine phosphorylation; entry of virus into host cell; defense response to Gram-positive bacterium; cell surface receptor linked signal transduction; tumor necrosis factor-mediated signaling pathway; T cell costimulation; positive regulation of cytokine secretion during immune response; negative regulation of alpha-beta T cell proliferation; immune response; defense response to Gram-negative bacterium
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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