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TNFRSF4 blocking peptide :: CD134 Blocking Peptide

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Catalog # MBS8204460
Unit / Price
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  1 mg  /  $160 +1 FREE 8GB USB
  5 mg  /  $305 +1 FREE 8GB USB
TNFRSF4 blocking peptide
Product Name

CD134 (TNFRSF4), Blocking Peptide

Full Product Name

CD134 Blocking Peptide

Product Synonym Names
TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD134
Antibody/Peptide Pairs
CD134 peptide (MBS8204460) is used for blocking the activity of CD134 antibody (MBS8232614)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
600315
3D Structure
ModBase 3D Structure for P43489
Host
Synthetic
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>85%
Form/Format
Lyophilized powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Directions for Use
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of TNFRSF4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
TNFRSF4 blocking peptide
The peptide is used to block Anti-CD134 Antibody reactivity.
Applications Tested/Suitable for TNFRSF4 blocking peptide
Blocking (BL)
NCBI/Uniprot data below describe general gene information for TNFRSF4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,341 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 4
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 4
NCBI Official Symbol
TNFRSF4  [Similar Products]
NCBI Official Synonym Symbols
OX40; ACT35; CD134; IMD16; TXGP1L
  [Similar Products]
NCBI Protein Information
tumor necrosis factor receptor superfamily member 4
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 4
UniProt Synonym Protein Names
ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD_antigen: CD134
UniProt Gene Name
TNFRSF4  [Similar Products]
UniProt Synonym Gene Names
TXGP1L  [Similar Products]
UniProt Entry Name
TNR4_HUMAN
NCBI Summary for TNFRSF4
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
UniProt Comments for TNFRSF4
TNFRSF4: Receptor for TNFSF4/OX40L/GP34.

Protein type: Membrane protein, integral; Apoptosis; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: cell surface; integral to plasma membrane; external side of plasma membrane

Molecular Function: tumor necrosis factor receptor activity

Biological Process: T cell proliferation; regulation of apoptosis; tumor necrosis factor-mediated signaling pathway; negative regulation of transcription factor activity; negative regulation of cytokine secretion; positive regulation of B cell proliferation; cellular defense response; immune response; positive regulation of immunoglobulin secretion; regulation of protein kinase activity; negative regulation of transcription, DNA-dependent; inflammatory response

Disease: Immunodeficiency 16
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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