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TNFRSF9 active protein :: Tumor necrosis factor receptor superfamily member 9 protein (TNFRSF9) Active Protein

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Catalog # MBS969313
Unit / Price
  0.005 mg  /  $115 +1 FREE 8GB USB
  0.02 mg  /  $205 +1 FREE 8GB USB
  0.1 mg  /  $430 +1 FREE 8GB USB
  0.25 mg  /  $725 +1 FREE 8GB USB
SDS-PAGE
Product Name

Tumor necrosis factor receptor superfamily member 9 protein (TNFRSF9), Active Protein

Popular Item
Also Known As

Recombinant Human Tumor necrosis factor receptor superfamily member 9 protein (TNFRSF9) (Active)

Product Synonym Names
4-1BB ligand receptor; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD antigen CD137
Product Synonym Gene Name
CD137; ILA[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
19-184aa, Partial
Sequence Length
255
Sequence
ERTRSLQDPC SNCPAGTFCD NNRNQICSPC PPNSFSSAGG QRTCDICRQC KGVFRTRKEC SSTSNAECDC TPGFHCLGAG CSMCEQDCKQ GQELTKKGCK DCCFGTFNDQ KRGICRPWTN CSLDGKSVLV NGTKERDVVC GPSPADLSPG ASSVTPPAPA REPGHS
OMIM
U03397 mRNA
3D Structure
ModBase 3D Structure for Q07011
Host
E Coli
Purity/Purification
>=97% as determined by SDS-PAGE and HPLC. (lot specific)
Form/Format
Lyophilized
Species
Homo sapiens (Human)
Biological Activity
Fully biologically active when compared to standard. The biological activity is determined by its inhibitory effect of IL-8 production using human peripheral blood mononuclear cells. About 90 % of inibition was seen using a concentration of 1 ug for both 4-1BB Ligand and 4-1BB Receptor.
Storage Buffer
0.2 um filtered PBS, pH 7.4,lyophilized
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Protein Note
Protein will be provided with aseptic processing and endotoxin removal.
Preparation and Storage
Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Active Protein Note
Refer to the datasheet for activity details. For other activity applications, researchers should evaluate this protein for suitability in their model system.
Other Notes
Small volumes of TNFRSF9 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
TNFRSF9 active protein
Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

TNFRSF9 active protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for TNFRSF9. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
17.7 kDa
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 9
NCBI Official Synonym Full Names
TNF receptor superfamily member 9
NCBI Official Symbol
TNFRSF9  [Similar Products]
NCBI Official Synonym Symbols
ILA; 4-1BB; CD137; CDw137
  [Similar Products]
NCBI Protein Information
tumor necrosis factor receptor superfamily member 9
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 9
UniProt Synonym Protein Names
4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD_antigen: CD137
UniProt Gene Name
TNFRSF9  [Similar Products]
UniProt Synonym Gene Names
CD137; ILA  [Similar Products]
NCBI Summary for TNFRSF9
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
UniProt Comments for TNFRSF9
TNFRSF9: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p36.23

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: receptor activity; tumor necrosis factor receptor activity

Biological Process: apoptosis; immune response; inflammatory response; multicellular organismal development; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with TNFRSF9 active protein
 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >7 publications with TNFRSF9 and Adipose Tissue
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