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TNFSF13B blocking peptide :: BAFF Blocking Peptide

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Catalog # MBS152973
Unit / Price
  0.05 mg  /  $140 +1 FREE 8GB USB
TNFSF13B blocking peptide
Product Name

BAFF (TNFSF13B), Blocking Peptide

Also Known As

BAFF Peptide

Product Synonym Names
DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; UNQ401/PRO738; Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; tumor necrosis factor (ligand) superfamily, member 13b
Antibody/Peptide Pairs
BAFF peptide (MBS152973) is used for blocking the activity of BAFF antibody (MBS150169)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
285
OMIM
603969
3D Structure
ModBase 3D Structure for Q9Y275
Form/Format
Liquid
Concentration
200 ug/mL (lot specific)
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
16 amino acids near the carboxy terminus of human BAFF.
Preparation and Storage
Store BAFF peptide at -20 degree C, stable for one year.
Other Notes
Small volumes of TNFSF13B blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for TNFSF13B blocking peptide
Blocking (BL)
Application Notes for TNFSF13B blocking peptide
BAFF peptide is used for blocking the activity of BAFF antibody.
NCBI/Uniprot data below describe general gene information for TNFSF13B. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,578 Da
NCBI Official Full Name
tumor necrosis factor ligand superfamily member 13B isoform 1
NCBI Official Synonym Full Names
tumor necrosis factor (ligand) superfamily, member 13b
NCBI Official Symbol
TNFSF13B  [Similar Products]
NCBI Official Synonym Symbols
DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
  [Similar Products]
NCBI Protein Information
tumor necrosis factor ligand superfamily member 13B; delta BAFF; Delta4 BAFF; B-lymphocyte stimulator; B-cell-activating factor; ApoL related ligand TALL-1; TNF homolog that activates apoptosis; dendritic cell-derived TNF-like molecule; tumor necrosis factor-like protein ZTNF4; TNF and ApoL-related leukocyte expressed ligand 1; tumor necrosis factor (ligand) superfamily, member 20
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 13B
UniProt Synonym Protein Names
B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; CD_antigen: CD257Cleaved into the following 2 chains:Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form
UniProt Gene Name
TNFSF13B  [Similar Products]
UniProt Synonym Gene Names
BAFF; BLYS; TALL1; TNFSF20; ZTNF4; BLyS; TALL-1  [Similar Products]
UniProt Entry Name
TN13B_HUMAN
NCBI Summary for TNFSF13B
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
UniProt Comments for TNFSF13B
BAFF: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Membrane protein, integral; Apoptosis; Cytokine

Chromosomal Location of Human Ortholog: 13q32-q34

Cellular Component: extracellular space; perinuclear region of cytoplasm; cytoplasm; integral to membrane; plasma membrane

Molecular Function: protein binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: cell proliferation; B cell costimulation; B cell homeostasis; immunoglobulin secretion; positive regulation of cell proliferation; T cell costimulation; positive regulation of germinal center formation; positive regulation of B cell proliferation; positive regulation of T cell proliferation; immune response; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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