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TNIP3 blocking peptide :: ABIN3 Blocking Peptide

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Catalog # MBS152909
Unit / Price
  0.05 mg  /  $140 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ABIN3 (TNIP3), Blocking Peptide

Popular Item
Also Known As

ABIN3 Peptide

Product Synonym Names
LIND; ABIN-3; ABIN3; LIND; TNFAIP3-interacting protein 3; A20-binding inhibitor of NF-kappa-B activation 3; TNFAIP3 interacting protein 3
Antibody/Peptide Pairs
ABIN3 peptide (MBS152909) is used for blocking the activity of ABIN3 antibody (MBS151164)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
325
OMIM
608019
3D Structure
ModBase 3D Structure for Q96KP6
Form/Format
Liquid
Concentration
200 ug/mL (lot specific)
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
17 amino acids near the carboxy terminus of human ABIN3.
Preparation and Storage
Store ABIN3 peptide at -20 degree C, stable for one year.
Other Notes
Small volumes of TNIP3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for TNIP3 blocking peptide
Blocking (BL)
Application Notes for TNIP3 blocking peptide
ABIN3 peptide is used for blocking the activity of ABIN3 antibody.

Western Blot (WB) of TNIP3 blocking peptide
Western blot analysis of ABIN3 in human spleen tissue lysate with ABIN3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
TNIP3 blocking peptide Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for TNIP3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,886 Da
NCBI Official Full Name
TNFAIP3-interacting protein 3 isoform 1
NCBI Official Synonym Full Names
TNFAIP3 interacting protein 3
NCBI Official Symbol
TNIP3  [Similar Products]
NCBI Official Synonym Symbols
LIND; ABIN-3
  [Similar Products]
NCBI Protein Information
TNFAIP3-interacting protein 3; TNIP3 beta; ABIN-3 beta; Listeria induced; listeria-induced gene protein; TNFAIP3-interacting protein 3 beta; A20-binding inhibitor of NF-kappa-B activation 3
UniProt Protein Name
TNFAIP3-interacting protein 3
UniProt Synonym Protein Names
A20-binding inhibitor of NF-kappa-B activation 3; ABIN-3; Listeria-induced gene protein
UniProt Gene Name
TNIP3  [Similar Products]
UniProt Synonym Gene Names
ABIN-3  [Similar Products]
UniProt Entry Name
TNIP3_HUMAN
UniProt Comments for TNIP3
TNIP3: Binds to zinc finger protein TNFAIP3 and inhibits NF- kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13- acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 4q27

Molecular Function: polyubiquitin binding

Biological Process: MyD88-independent toll-like receptor signaling pathway; negative regulation of I-kappaB kinase/NF-kappaB cascade; inflammatory response; toll-like receptor 4 signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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