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TNKS elisa kit :: Human tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase ELISA Kit

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Catalog # MBS9318040
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
TNKS elisa kit
Product Name

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (TNKS), ELISA Kit

Also Known As

Human Tankyrase-1, TNKS ELISA Kit

Product Synonym Names
Human Tankyrase-1 (TNKS) ELISA kit; PARP-5a; PARP5A; PARPL; TIN1; TINF1; TNKS1; ; tankyrase; TRF1-interacting ankyrin-related ADP-ribose polymerase
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
603303
3D Structure
ModBase 3D Structure for O95271
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of TNKS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forTNKSpurchase
MBS9318040 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (TNKS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TNKS. The ELISA analytical biochemical technique of the MBS9318040 kit is based on TNKS antibody-TNKS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNKS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TNKS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for TNKS. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
142,039 Da
NCBI Official Full Name
tankyrase-1
NCBI Official Synonym Full Names
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
NCBI Official Symbol
NCBI Official Synonym Symbols
TIN1; ARTD5; PARPL; TINF1; TNKS1; pART5; PARP5A; PARP-5a
  [Similar Products]
NCBI Protein Information
tankyrase-1; TANK1; TNKS-1; tankyrase I; poly [ADP-ribose] polymerase 5A; ADP-ribosyltransferase diphtheria toxin-like 5; TRF1-interacting ankyrin-related ADP-ribose polymerase
UniProt Protein Name
Tankyrase-1
UniProt Synonym Protein Names
ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; Poly [ADP-ribose] polymerase 5A; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase I
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
PARP5A; PARPL; TIN1; TINF1; TNKS1; TANK1; ARTD5  [Similar Products]
UniProt Entry Name
TNKS1_HUMAN
UniProt Comments for TNKS
TNKS: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.4.2.30

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: Golgi membrane; Golgi apparatus; spindle pole; chromosome, telomeric region; pericentriolar material; nuclear membrane; nuclear chromosome, telomeric region; nuclear pore; cytosol; chromosome, pericentric region

Molecular Function: protein binding; zinc ion binding; NAD+ ADP-ribosyltransferase activity

Biological Process: mitosis; mRNA transport; Wnt receptor signaling pathway; protein polyubiquitination; peptidyl-threonine phosphorylation; spindle assembly; negative regulation of DNA binding; positive regulation of telomere maintenance via telomerase; peptidyl-serine phosphorylation; protein transport; protein amino acid ADP-ribosylation; mitotic spindle organization and biogenesis; cell division; positive regulation of transcription from RNA polymerase II promoter; regulation of telomere maintenance via telomerase
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with TNKS elisa kit
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