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TNP1 cdna clone

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Catalog # MBS1275042
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
TNP1 cdna clone
Product Name

TNP1, cDNA Clone

Popular Item
Also Known As

TNP1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
168
Sequence
atgtcgacca gccgcaaatt aaagagtcat ggcatgagga ggagcaagag ccgatctcct cacaagggag tcaagagagg tggcagcaaa agaaaatacc gtaagggcaa cctgaaaagt aggaaacggg gcgatgacgc caatcgcaat taccgctccc acttgtga
OMIM
190231
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of TNP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TNP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
Molecular Weight
6,424 Da
NCBI Official Full Name
Homo sapiens transition protein 1 (during histone to protamine replacement), mRNA
NCBI Official Synonym Full Names
transition protein 1
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
spermatid nuclear transition protein 1
UniProt Protein Name
Spermatid nuclear transition protein 1
UniProt Gene Name
UniProt Synonym Gene Names
STP-1; TP-1  [Similar Products]
UniProt Entry Name
STP1_HUMAN
NCBI Summary for TNP1
Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008]
UniProt Comments for TNP1
TP1: In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins. Belongs to the nuclear transition protein 1 family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 2q35-q36

Cellular Component: male germ cell nucleus; nucleosome

Molecular Function: DNA binding; protein binding

Biological Process: chromatin remodeling; chromatin silencing; fertilization, exchange of chromosomal proteins; negative regulation of transcription, DNA-dependent; nucleosome disassembly; sexual reproduction; single strand break repair; sperm motility; spermatid development; spermatid nuclear differentiation; spermatid nuclear elongation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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