NP_061978.6
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
458,535 Da
NCBI Official Full Name
tenascin-X isoform 1
NCBI Official Synonym Full Names
tenascin XB
NCBI Official Synonym Symbols
XB; TNX; XBS; EDS3; HXBL; TENX; TN-X; VUR8; TNXB1; TNXB2; TNXBS; EDSCLL [Similar Products]
NCBI Protein Information
tenascin-X
UniProt Protein Name
Tenascin-X
UniProt Synonym Protein Names
Hexabrachion-like protein
UniProt Synonym Gene Names
NCBI Summary for TNXB
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for TNXB
Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors.
Research Articles on TNXB
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Products associated with TNXB recombinant protein
Pathways associated with TNXB recombinant protein
Diseases associated with TNXB recombinant protein
Organs/Tissues associated with TNXB recombinant protein
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