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TRAIL recombinant protein :: Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL) Recombinant Protein

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Catalog # MBS2009976 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $140 +1 FREE 8GB USB
  0.05 mg  /  $260 +1 FREE 8GB USB
  0.1 mg  /  $400 +1 FREE 8GB USB
  0.2 mg  /  $495 +1 FREE 8GB USB
  0.5 mg  /  $955 +1 FREE 8GB USB
  1 mg  /  $1,415 +1 FREE 8GB USB
Product Name

Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL), Recombinant Protein

Popular Item
Also Known As

Recombinant Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
291
Sequence
The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MHHHHHHSSG LVPRGSGMKE TAAAKF ERQHMDSPDL GTDDDDKAMA DIGSEF-M YFTNEMKQLQ DNYSKIGLAC FSKTDEDFWD STDGEILNRP CLQVKRQLYQ LIEEVTLRTF QDTISTVPEK QLSTPPLPRG GRPQKVAAHI TGITRRSNSA LIPISKDGKT LGQKIESWES SRKGHSFLNH VLFRNGELVI EQEGLYYIYS QTYFRFQEAE DASKMVSKDK VRTKQLVQYI YKYTSYPDPI VLMKSARNSC WSRDAEYGLY SIYQGGLFEL KKNDRIFVSV TNEHLMDLDQ EASFFGAFLI N
Chromosome Location
Chromosome: 3; NC_000069.6 (27317077..27339665). Location: 3 A3; 3
3D Structure
ModBase 3D Structure for P50592
Host
E Coli
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Organism
Mus musculus (Mouse)
Expression System
Prokaryotic expression
Residues
Met40~Asn291 (Accession # P50592) with two N-terminal Tags, His-tag and T7-tag
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
Other Notes
Small volumes of TRAIL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
TRAIL recombinant protein
About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
Applications Tested/Suitable for TRAIL recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Sequence Information of TRAIL recombinant protein
TRAIL recombinant protein Sequence Information image
TRAIL recombinant protein Testing Data image
NCBI/Uniprot data below describe general gene information for TRAIL. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
34.9kDa
NCBI Official Full Name
tumor necrosis factor ligand superfamily member 10
NCBI Official Synonym Full Names
tumor necrosis factor (ligand) superfamily, member 10
NCBI Official Symbol
Tnfsf10  [Similar Products]
NCBI Official Synonym Symbols
TL2; Ly81; Trail; APO-2L; AI448571; A330042I21Rik
  [Similar Products]
NCBI Protein Information
tumor necrosis factor ligand superfamily member 10; TRAIL/APO2L; TNF-related apoptosis inducing ligand; TNF-related apoptosis-inducing ligand
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 10
UniProt Synonym Protein Names
TNF-related apoptosis-inducing ligand
UniProt Gene Name
Tnfsf10  [Similar Products]
UniProt Synonym Gene Names
Trail; Protein TRAIL  [Similar Products]
UniProt Entry Name
TNF10_MOUSE
UniProt Comments for TRAIL
TRAIL: Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. Homotrimer. Widespread; most predominant in spleen, lung and prostate. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cytokine

Cellular Component: extracellular space; membrane; integral to membrane

Molecular Function: cytokine activity; tumor necrosis factor receptor superfamily binding; tumor necrosis factor receptor binding

Biological Process: positive regulation of apoptosis; apoptosis; positive regulation of caspase activity; immune response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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