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TRIM8 peptide :: GERP / TRIM8 Peptide

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Catalog # MBS426744
Unit / Price
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  0.1 mg  /  $190 +1 FREE 8GB USB
TRIM8 peptide
Product Name

GERP / TRIM8, Peptide

Full Product Name

GERP / TRIM8 Immunizing Peptide

Product Synonym Names
TRIM8; tripartite motif-containing 8; GERP; RNF27; ring finger protein 27; tripartite motif protein TRIM8; glioblastoma expressed ring finger protein; RP11-47A8.4; GERP / TRIM8
Product Gene Name
Product Synonym Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
C-YGQPSTKH YVTS
OMIM
606125
Species Reactivity
Human, Mouse, Rat, Dog, Pig
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of TRIM8 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TRIM8. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
61,489 Da
NCBI Official Full Name
probable E3 ubiquitin-protein ligase TRIM8
NCBI Official Synonym Full Names
tripartite motif containing 8
NCBI Official Symbol
TRIM8  [Similar Products]
NCBI Official Synonym Symbols
GERP; RNF27
  [Similar Products]
NCBI Protein Information
probable E3 ubiquitin-protein ligase TRIM8
UniProt Protein Name
Probable E3 ubiquitin-protein ligase TRIM8
UniProt Synonym Protein Names
Glioblastoma-expressed RING finger protein; RING finger protein 27; Tripartite motif-containing protein 8
UniProt Gene Name
TRIM8  [Similar Products]
UniProt Synonym Gene Names
GERP; RNF27  [Similar Products]
UniProt Entry Name
TRIM8_HUMAN
NCBI Summary for TRIM8
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008]
UniProt Comments for TRIM8
TRIM8: Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1. Belongs to the TRIM/RBCC family.

Protein type: Ubiquitin conjugating system; EC 6.3.2.-; Ligase; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 10q24.3

Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleoplasm; PML body

Molecular Function: identical protein binding; ligase activity; protein homodimerization activity; zinc ion binding

Biological Process: activation of NF-kappaB transcription factor; innate immune response; negative regulation of viral transcription; negative regulation of virion penetration into host cell; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity; protein ubiquitination; stem cell maintenance
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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