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TRPM1 cdna clone

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Catalog # MBS1266236
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
TRPM1 cdna clone
Product Name

TRPM1, cDNA Clone

Popular Item
Also Known As

TRPM1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
411
Sequence
atgaaagact ctaacaggtg ttgctgtggc cagttcacca accagcatat cccccctctg ccaagtgcaa cacccagcaa aaatgaagag gaaaacaaac aggtggagac tcagcctgag aaatggtctg ttgccaagca cacccagagc tacccaacag attcctatgg agttcttgaa ttccagggtg gcggatattc caataaagcc atggtgagaa aggcattcag acatggtgcc actaggatca cagctttcat tggcggccag tctcccagcc ccaaactgca gatacctggt cttcttcatg gctgtggctc aatcttccta gatatttcat tgaaaaacca agagatatat ctgtgcacat ggcttttagc catgaggctt ggaaactgga caccactgta a
OMIM
603576
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of TRPM1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TRPM1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,099 Da
NCBI Official Full Name
Homo sapiens transient receptor potential cation channel, subfamily M, member 1, mRNA
NCBI Official Synonym Full Names
transient receptor potential cation channel subfamily M member 1
NCBI Official Symbol
TRPM1  [Similar Products]
NCBI Official Synonym Symbols
MLSN1; CSNB1C; LTRPC1
  [Similar Products]
NCBI Protein Information
transient receptor potential cation channel subfamily M member 1
UniProt Protein Name
Transient receptor potential cation channel subfamily M member 1
UniProt Synonym Protein Names
Long transient receptor potential channel 1; LTrpC1; Melastatin-1
UniProt Gene Name
TRPM1  [Similar Products]
UniProt Synonym Gene Names
LTrpC1  [Similar Products]
UniProt Entry Name
TRPM1_HUMAN
NCBI Summary for TRPM1
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
UniProt Comments for TRPM1
TRPM1: a transient receptor potential (TRP) ion channel. TRP voltage-independent calcium-permeable cation channels are divided into six subfamilies, two of which (TRPC and TRPM) have members that are widely expressed. Its expression is inversely correlated with melanoma aggressiveness, suggesting that it suppresses melanoma metastasis.

Protein type: Membrane protein, integral; Channel, calcium; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 15q13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: calcium channel activity

Biological Process: metabotropic glutamate receptor signaling pathway; transport; visual perception

Disease: Night Blindness, Congenital Stationary, Type 1c
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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