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TRPV1 blocking peptide

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Catalog # MBS824306
Unit / Price
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  1 mg  /  $160 +1 FREE 8GB USB
  5 mg  /  $305 +1 FREE 8GB USB
TRPV1 blocking peptide
Product Name

TRPV1, Blocking Peptide

Popular Item
Full Product Name

TRPV1 Blocking Peptide

Product Synonym Names
VR1; Transient receptor potential cation channel subfamily V member 1; TrpV1; Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1
Antibody/Peptide Pairs
TRPV1 peptide (MBS824306) is used for blocking the activity of TRPV1 antibody (MBS820843)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602076
3D Structure
ModBase 3D Structure for Q8NER1
Host
Synthetic
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>85%
Form/Format
Lyophilized powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Entrez Gene
7442 (Human); 193034 (Mouse); 83810 (Rat)
SwissProt
Q8NER1 (Human); Q704Y3 (Mouse); O35433 (Rat)
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of TRPV1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
TRPV1 blocking peptide
The peptide is used to block Anti-TRPV1 Antibody reactivity.
Applications Tested/Suitable for TRPV1 blocking peptide
Blocking (BL)
Application Notes for TRPV1 blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
NCBI/Uniprot data below describe general gene information for TRPV1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
94,211 Da
NCBI Official Full Name
transient receptor potential cation channel subfamily V member 1
NCBI Official Synonym Full Names
transient receptor potential cation channel, subfamily V, member 1
NCBI Official Symbol
TRPV1  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
transient receptor potential cation channel subfamily V member 1; OTRPC1; capsaicin receptor; osm-9-like TRP channel 1; vanilloid receptor subtype 1; transient receptor potential vanilloid 1a; transient receptor potential vanilloid 1b
UniProt Protein Name
Transient receptor potential cation channel subfamily V member 1
UniProt Synonym Protein Names
Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1
UniProt Gene Name
TRPV1  [Similar Products]
UniProt Synonym Gene Names
VR1; TrpV1; OTRPC1  [Similar Products]
UniProt Entry Name
TRPV1_HUMAN
NCBI Summary for TRPV1
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for TRPV1
TRPV1: a receptor for capsaicin and a non-selective cation channel that is structurally related to members of the TRP family of ion channels. Activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.

Protein type: Channel, cation; Membrane protein, multi-pass; Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; integral to membrane; cell junction; intrinsic to plasma membrane

Molecular Function: calmodulin binding; transmembrane receptor activity; excitatory extracellular ligand-gated ion channel activity; calcium channel activity; calcium-release channel activity; phosphoprotein binding; ATP binding

Biological Process: cell surface receptor linked signal transduction; transport; chemosensory behavior; thermoception; transmembrane transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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