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TSC1 peptide :: Hamartin / TSC1 Peptide

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Catalog # MBS426893
Unit / Price
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  0.1 mg  /  $190 +1 FREE 8GB USB
TSC1 peptide
Product Name

Hamartin / TSC1, Peptide

Full Product Name

Hamartin / TSC1 Immunizing Peptide

Product Synonym Names
TSC1; hamartin; tuberous sclerosis 1; HGNC: 12362; KIAA0243; LAM; MGC86987; TSC; tuberous sclerosis 1 protein; tumor suppressor; Hamartin; Hamartin / TSC1 (isoform 1)
Product Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat, Dog
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of TSC1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TSC1. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
124,015 Da
NCBI Official Full Name
hamartin isoform 1
NCBI Official Synonym Full Names
tuberous sclerosis 1
NCBI Official Symbol
NCBI Official Synonym Symbols
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NCBI Protein Information
UniProt Protein Name
UniProt Synonym Protein Names
Tuberous sclerosis 1 protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
KIAA0243; TSC  [Similar Products]
UniProt Entry Name
NCBI Summary for TSC1
This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
UniProt Comments for TSC1
TSC1: tuberous sclerosis protein 1 (TSC1). May have tumor suppressor activity. Together with tuberin (TSC2), inhibits mammalian target of rapamycin (mTOR)-mediated signaling to eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) and ribosomal protein S6 kinase. Regulated by the phosphatidylinositol 3-kinase/Akt pathway and phosphorylation of tuberin. Phosphorylated by cyclin-dependent kinase 1/cyclin B during the cell cycle.

Protein type: Tumor suppressor; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: actin filament; cell cortex; cytoplasm; cytosol; growth cone; lamellipodium; membrane; nucleus; perinuclear region of cytoplasm; plasma membrane; protein complex; TSC1-TSC2 complex

Molecular Function: chaperone binding; GTPase activating protein binding; GTPase regulator activity; protein binding; protein N-terminus binding

Biological Process: adaptive immune response; adult locomotory behavior; cardiac muscle cell differentiation; cell cycle arrest; cell projection organization and biogenesis; cell-matrix adhesion; cerebral cortex development; glucose import; hippocampus development; kidney development; memory T cell differentiation; myelination; negative regulation of cell proliferation; negative regulation of cell size; negative regulation of insulin receptor signaling pathway; negative regulation of macroautophagy; negative regulation of TOR signaling pathway; negative regulation of translation; neural tube closure; positive regulation of focal adhesion formation; potassium ion transport; protein heterooligomerization; protein stabilization; regulation of cell cycle; regulation of cell-matrix adhesion; regulation of phosphoprotein phosphatase activity; regulation of protein kinase activity; regulation of stress fiber formation; regulation of translation; response to insulin stimulus; rRNA export from nucleus; synapse organization and biogenesis

Disease: Focal Cortical Dysplasia Of Taylor; Lymphangioleiomyomatosis; Tuberous Sclerosis 1
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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