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TUBA4A blocking peptide

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Catalog # MBS9219982
Unit / Price
  0.1 mg  /  $155 +1 FREE 8GB USB
TUBA4A blocking peptide
Product Name

TUBA4A, Blocking Peptide

Also Known As

TUBA4A Antibody (C-term) Blocking peptide

Product Synonym Names
Tubulin alpha-4A chain; Alpha-tubulin 1; Testis-specific alpha-tubulin; Tubulin H2-alpha; Tubulin alpha-1 chain; TUBA4A; TUBA1
Product Synonym Gene Name
Antibody/Peptide Pairs
TUBA4A peptide (MBS9219982) is used for blocking the activity of TUBA4A antibody (MBS9212231)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
448
OMIM
191110
3D Structure
ModBase 3D Structure for P68366
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of TUBA4A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Cytoplasm, cytoskeleton.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of TUBA4A blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
TUBA4A blocking peptide
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
NCBI/Uniprot data below describe general gene information for TUBA4A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,329 Da
NCBI Official Full Name
Tubulin alpha-4A chain
NCBI Official Synonym Full Names
tubulin alpha 4a
NCBI Official Symbol
TUBA4A  [Similar Products]
NCBI Official Synonym Symbols
ALS22; TUBA1; H2-ALPHA
  [Similar Products]
NCBI Protein Information
tubulin alpha-4A chain
UniProt Protein Name
Tubulin alpha-4A chain
UniProt Synonym Protein Names
Alpha-tubulin 1; Testis-specific alpha-tubulin; Tubulin H2-alpha; Tubulin alpha-1 chain
Protein Family
UniProt Gene Name
TUBA4A  [Similar Products]
UniProt Synonym Gene Names
TUBA1  [Similar Products]
UniProt Entry Name
TBA4A_HUMAN
NCBI Summary for TUBA4A
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
UniProt Comments for TUBA4A
TUBA4A: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Belongs to the tubulin family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: cytosol; extracellular region; microtubule

Molecular Function: protein binding

Biological Process: G2/M transition of mitotic cell cycle; platelet degranulation

Disease: Amyotrophic Lateral Sclerosis 22 With Or Without Frontotemporal Dementia
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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