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UBE2R2 recombinant protein :: Ubiquitin Conjugating Enzyme E2R 2 Recombinant Protein

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Catalog # MBS144008
Unit / Price
  0.002 mg  /  $140 +1 FREE 8GB USB
  0.01 mg  /  $205 +1 FREE 8GB USB
  1 mg  /  $5,015 +6 FREE 8GB USB
UBE2R2 recombinant protein
Product Name

Ubiquitin Conjugating Enzyme E2R 2 (UBE2R2), Recombinant Protein

Popular Item
Also Known As

Recombinant Human Ubiquitin Conjugating Enzyme E2R 2

Product Synonym Names
UBE2R2 Human; Ubiquitin Conjugating Enzyme E2R 2 Human Recombinant; CDC34B; E2-CDC34B; UBC3B; Ubiquitin carrier protein R2; Ubiquitin-conjugating enzyme E2-CDC34B; Ubiquitin-protein ligase R2; Ubiquitin-conjugating enzyme E2 R2; EC 6.3.2.19
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
238
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMAQ QQMT SSQKALMLEL KSLQEEPVEG FRITLVDESD LYNWEVAIFG PPNTLYEGGY FKAHIKFPID YPYSPPTFRF LTKMWHPNIY ENGDVCISIL HPPVDDPQSG ELPSERWNPT QNVRTILLSV ISLLNEPNTF SPANVDASVM FRKWRDSKGK DKEYAEIIRK QVSATKAEAE KDGVKVPTTL AEYCIKTKVP SNDNSSDLLY DDLYDDDIDD EDEEEEDADC YDDDDSGNEE S
OMIM
612506
3D Structure
ModBase 3D Structure for Q712K3
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
UBE2R2 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
Sterile Filtered clear solution.
Other Notes
Small volumes of UBE2R2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
UBE2R2 recombinant protein
Description: UBE2R2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 261 amino acids (1-238 a.a) and having a molecular mass of 29.6kDa (Molecular size on SDS-PAGE will appear higher).UBE2R2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: Ubiquitin-conjugating enzyme E2 R2 (UBE2R2) is a member of the ubiquitin-conjugating enzyme family. Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr
NCBI/Uniprot data below describe general gene information for UBE2R2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,166 Da
NCBI Official Full Name
ubiquitin-conjugating enzyme E2 R2
NCBI Official Synonym Full Names
ubiquitin-conjugating enzyme E2R 2
NCBI Official Symbol
UBE2R2  [Similar Products]
NCBI Official Synonym Symbols
UBC3B; CDC34B; E2-CDC34B
  [Similar Products]
NCBI Protein Information
ubiquitin-conjugating enzyme E2 R2; ubiquitin carrier protein R2; ubiquitin-conjugating enzyme E2-CDC34B; ubiquitin-conjugating enzyme UBC3B; ubiquitin-protein ligase R2
UniProt Protein Name
Ubiquitin-conjugating enzyme E2 R2
UniProt Synonym Protein Names
Ubiquitin carrier protein R2; Ubiquitin-conjugating enzyme E2-CDC34B; Ubiquitin-protein ligase R2
UniProt Gene Name
UBE2R2  [Similar Products]
UniProt Synonym Gene Names
CDC34B; UBC3B  [Similar Products]
UniProt Entry Name
UB2R2_HUMAN
NCBI Summary for UBE2R2
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]
UniProt Comments for UBE2R2
UBC3B: an E2 ubiquitin conjugating enzyme similar to UBC3/CDC34. Phosphorylation of UBC3B by CK2 induces its interaction with beta-TrCP, regulating beta-TrCP substrate recognition and enhancing beta-catenin degradation.

Protein type: Ubiquitin ligase; Ligase; Ubiquitin conjugating system; EC 6.3.2.19

Chromosomal Location of Human Ortholog: 9p13.3

Cellular Component: cytoplasm

Molecular Function: small conjugating protein ligase activity; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; ATP binding; ligase activity

Biological Process: protein monoubiquitination; proteasomal ubiquitin-dependent protein catabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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