NP_057411
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
beta-ureidopropionase
NCBI Official Synonym Full Names
beta-ureidopropionase 1
NCBI Official Synonym Symbols
NCBI Protein Information
beta-ureidopropionase
UniProt Protein Name
Beta-ureidopropionase
UniProt Synonym Protein Names
BUP-1; Beta-alanine synthase; N-carbamoyl-beta-alanine amidohydrolase
UniProt Synonym Gene Names
NCBI Summary for UPB1
This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]
UniProt Comments for UPB1
Converts N-carbamoyl-beta-aminoisobutyrate and N-carbamoyl-beta-alanine (3-ureidopropanoate) to, respectively, beta-aminoisobutyrate and beta-alanine, ammonia and carbon dioxide.
Research Articles on UPB1
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Products associated with UPB1 blocking peptide
Pathways associated with UPB1 blocking peptide
Diseases associated with UPB1 blocking peptide
Organs/Tissues associated with UPB1 blocking peptide
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