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UQCRQ elisa kit :: Mouse Cytochrome b-c1 complex subunit 8 (UQCRQ) ELISA Kit

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Catalog # MBS7241580
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UQCRQ elisa kit
Product Name

Cytochrome b-c1 complex subunit 8 (UQCRQ), ELISA Kit

Full Product Name

Mouse Cytochrome b-c1 complex subunit 8 (UQCRQ) ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
gene 615159
Species Reactivity
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Preparation and Storage
Store all reagents at 2-8 degree C.
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of UQCRQ elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for UQCRQpurchase
MBS7241580 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cytochrome b-c1 complex subunit 8 (UQCRQ) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing UQCRQ. The ELISA analytical biochemical technique of the MBS7241580 kit is based on UQCRQ antibody-UQCRQ antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect UQCRQ antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, UQCRQ. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for UQCRQ. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
9,906 Da
NCBI Official Full Name
cytochrome b-c1 complex subunit 8
NCBI Official Synonym Full Names
ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
NCBI Official Symbol
UQCRQ  [Similar Products]
NCBI Official Synonym Symbols
QPC; QCR8; QP-C; UQCR7; MC3DN4
  [Similar Products]
NCBI Protein Information
cytochrome b-c1 complex subunit 8; complex III subunit 8; complex III subunit VIII; low molecular mass ubiquinone-binding protein (9.5kD); ubiquinol-cytochrome c reductase complex 9.5 kDa protein; ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
UniProt Protein Name
Cytochrome b-c1 complex subunit 8
UniProt Synonym Protein Names
Complex III subunit 8; Complex III subunit VIII; Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
UniProt Gene Name
UQCRQ  [Similar Products]
UniProt Entry Name
QCR8_HUMAN
NCBI Summary for UQCRQ
This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008]
UniProt Comments for UQCRQ
UQCRQ: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone. Defects in UQCRQ are a cause of mitochondrial complex III deficiency (MT-C3D). A disorder of the mitochondrial respiratory chain resulting in a highly variable phenotype depending on which tissues are affected. Clinical features include mitochondrial encephalopathy, psychomotor retardation, ataxia, severe failure to thrive, liver dysfunction, renal tubulopathy, muscle weakness and exercise intolerance. Belongs to the UQCRQ/QCR8 family.

Protein type: Oxidoreductase; Mitochondrial; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: mitochondrion; mitochondrial inner membrane

Molecular Function: ubiquinol-cytochrome-c reductase activity

Biological Process: cellular metabolic process; hypothalamus development; pons development; hippocampus development; midbrain development; cerebellar Purkinje cell layer development; subthalamus development; pyramidal neuron development; thalamus development

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 4
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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